EPSTI1

Description		epithelial stromal interaction 1
Image		No pdb structure
GO Annotations	Cellular Component
	Molecular Function	Protein Binding
	Biological Process
Pathways		RND1 GTPase cycle
Drugs
Diseases
GWAS		Age-related cognitive decline (executive function) (slope of z-scores) ( 30954325) Dimensional psychopathology (Arousal) ( 29496196) Heel bone mineral density ( 30598549) Irritable bowel syndrome ( 29626450) Obesity-related traits ( 23251661) Response to cognitive-behavioural therapy in anxiety and major depressive disorders ( 31123309) Severe aplastic anemia ( 32004448)
Interacting Genes		13 interacting genes: AKT1 AURKA BAG4 BCAR3 CASP8 ESR1 FGFR4 FZR1 NOTCH2 PPM1D PTPRJ RB1CC1 VCP
Entrez ID		94240
HPRD ID		06309
Ensembl ID		ENSG00000133106
Uniprot IDs		Q96J88
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Intracellular Signal Transduction Positive Regulation Of Proteolysis Regulation Of Signal Transduction Positive Regulation Of Intracellular Signal Transduction Regulation Of Cell Communication Regulation Of Signaling Regulation Of Proteolysis Positive Regulation Of Signal Transduction Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Cell Population Proliferation Positive Regulation Of Cell Communication Positive Regulation Of Signaling Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Programmed Cell Death Regulation Of Catalytic Activity Regulation Of Apoptotic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Catalytic Activity Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Regulation Of Programmed Cell Death Positive Regulation Of Anaphase-promoting Complex-dependent Catabolic Process Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Anaphase-promoting Complex-dependent Catabolic Process Signal Transduction Nitric-oxide Synthase Regulator Activity Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Protein Metabolic Process Positive Regulation Of Protein Catabolic Process Protein Kinase Binding Positive Regulation Of MAPK Cascade Positive Regulation Of Metabolic Process Negative Regulation Of Apoptotic Process Animal Organ Development Positive Regulation Of Cell Population Proliferation Regulation Of Metabolic Process Positive Regulation Of Catabolic Process Regulation Of Primary Metabolic Process Regulation Of Protein Metabolic Process Ubiquitin Protein Ligase Binding Positive Regulation Of Fibroblast Migration Liver Development Protein Modification Process Positive Regulation Of Macromolecule Metabolic Process Enzyme-linked Receptor Protein Signaling Pathway Regulation Of MAPK Cascade Protein Autophosphorylation Response To Tumor Necrosis Factor Proteolysis Involved In Protein Catabolic Process Mitogen-activated Protein Kinase Binding
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