HTRA3

Description		HtrA serine peptidase 3
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GO Annotations	Cellular Component	Extracellular Region
	Molecular Function	Endopeptidase Activity Serine-type Endopeptidase Activity Protein Binding Peptidase Activity Serine-type Peptidase Activity Hydrolase Activity Identical Protein Binding
	Biological Process	Proteolysis Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of BMP Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Response to cognitive-behavioural therapy in major depressive disorder ( 31123309)
Novel Interacting Genes		1 novel interacting genes: JAKMIP1
Interacting Genes		1 interacting genes: XIAP
Entrez ID		94031
HPRD ID		08821
Ensembl ID		ENSG00000170801
Uniprot IDs		P83110
PDB IDs		2P3W 4RI0
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Protein Linear Polyubiquitination Regulation Of Apoptosis Involved In Tissue Homeostasis Nucleotide-binding Oligomerization Domain Containing 1 Signaling Pathway Protein Linear Polyubiquitination Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Nucleotide-binding Oligomerization Domain Containing 2 Signaling Pathway Regulation Of Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Positive Regulation Of Protein Polyubiquitination Copper Ion Homeostasis Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process GABA Receptor Binding Execution Phase Of Apoptosis P38MAPK Cascade Protein Serine/threonine Kinase Binding Regulation Of Protein Polyubiquitination Cysteine-type Endopeptidase Inhibitor Activity Negative Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway
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