SP140L

Description		SP140 nuclear body protein like
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Defense Response
Pathways
Drugs
Diseases
GWAS		Cholangiocarcinoma in primary sclerosing cholangitis (time to event) ( 28779025) Lymphocyte percentage of white cells ( 32888494) Nicotine use ( 23942779) Night sleep phenotypes ( 27126917)
Interacting Genes		2 interacting genes: APP NEDD4
Entrez ID		93349
HPRD ID		14299
Ensembl ID		ENSG00000185404
Uniprot IDs		H7BYP4 Q9H930 U5Y1J8 U5Y3L1
PDB IDs
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Regulation Of Spontaneous Synaptic Transmission Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Response To Metal Ion Regulation Of Synapse Organization Response To Light Stimulus Intermediate-density Lipoprotein Particle Regulation Of Monoatomic Ion Transport Enzyme Binding Regulation Of Response To Calcium Ion Axon Midline Choice Point Recognition Regulation Of Membrane Potential NMDA Selective Glutamate Receptor Signaling Pathway Amylin Binding Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of Protein Catabolic Process Regulation Of Synapse Structure Or Activity Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Regulation Of Toll Signaling Pathway Regulation Of Monoatomic Ion Transmembrane Transport Endocytosis Regulation Of Protein Catabolic Process Regulation Of Metal Ion Transport Lipoprotein Particle Growth Factor Receptor Binding Main Axon Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Response To Radiation Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Regulation Of Monoatomic Cation Transmembrane Transport Synapse Organization Nuclear Receptor-mediated Glucocorticoid Signaling Pathway Channel Inhibitor Activity Phosphoserine Residue Binding
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