KCNB2

Description		potassium voltage-gated channel subfamily B member 2
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Voltage-gated Potassium Channel Complex Membrane Dendrite Neuronal Cell Body Membrane Monoatomic Ion Channel Complex Cell Projection Neuronal Cell Body Perikaryon
	Molecular Function	Monoatomic Ion Channel Activity Voltage-gated Potassium Channel Activity Delayed Rectifier Potassium Channel Activity Potassium Channel Activity Protein Binding Potassium Channel Regulator Activity Protein Heterodimerization Activity
	Biological Process	Action Potential Monoatomic Ion Transport Potassium Ion Transport Regulation Of Smooth Muscle Contraction Monoatomic Ion Transmembrane Transport Protein Homooligomerization Transmembrane Transport Potassium Ion Transmembrane Transport Protein Localization To Plasma Membrane
Pathways		Voltage gated Potassium channels
Drugs		Enflurane Promethazine Miconazole Dalfampridine
Diseases
GWAS		Adult body size ( 32376654) Chronotype ( 30696823) Cognitive performance ( 20125193) Coronary artery disease in type 1 diabetes ( 29695241) Crohn's disease ( 22412388) Echocardiographic traits ( 17903301) HDL cholesterol levels ( 32203549) Multiple sclerosis (age of onset) ( 19010793) Tea consumption ( 31046077) Type 2 diabetes ( 32499647)
Interacting Genes		4 interacting genes: KCNB1 KCNG3 KCNV1 VAPA
Entrez ID		9312
HPRD ID		09666
Ensembl ID		ENSG00000182674
Uniprot IDs		Q92953
PDB IDs
Enriched GO Terms of Interacting Partners?		Potassium Channel Regulator Activity Voltage-gated Potassium Channel Activity Potassium Channel Activity Voltage-gated Potassium Channel Complex Action Potential Monoatomic Ion Channel Complex Potassium Ion Transmembrane Transport Monoatomic Ion Channel Activity Potassium Ion Transport Protein Homooligomerization Protein Complex Oligomerization Regulation Of Membrane Potential Organelle Localization By Membrane Tethering Membrane Docking Metal Ion Transport Monoatomic Cation Transmembrane Transport Inorganic Cation Transmembrane Transport Inorganic Ion Transmembrane Transport Monoatomic Cation Transport Monoatomic Ion Transmembrane Transport Monoatomic Ion Transport Positive Regulation Of Norepinephrine Secretion FFAT Motif Binding Clustering Of Voltage-gated Potassium Channels Transmembrane Transport COPII-coated Vesicle Budding Endoplasmic Reticulum-plasma Membrane Tethering Protein-containing Complex Assembly Positive Regulation Of Long-term Synaptic Depression Endoplasmic Reticulum Localization Proximal Dendrite Protein-containing Complex Organization Cholinergic Synapse Neuronal Ion Channel Clustering Protein Heterodimerization Activity Host-mediated Activation Of Viral Genome Replication Sphingomyelin Biosynthetic Process Host-mediated Perturbation Of Viral Genome Replication Regulation Of Norepinephrine Secretion Positive Regulation Of Catecholamine Secretion Protein Folding In Endoplasmic Reticulum Host-mediated Suppression Of Viral Genome Replication Ion Channel Inhibitor Activity Regulation Of Motor Neuron Apoptotic Process Regulation Of Long-term Synaptic Depression Potassium Ion Export Across Plasma Membrane Positive Regulation Of Calcium Ion-dependent Exocytosis Outward Rectifier Potassium Channel Activity Protein Localization To Endoplasmic Reticulum Ceramide Transport
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