DMKN

Name	dermokine
Structure
Interactors	7 interactors: APP BAG6 GAD2 SGTA SGTB UBQLN1 UBQLN2
GO Annotations	Cellular Component	Extracellular Region Extracellular Space
	Molecular Function	Protein Binding
	Biological Process	Cornified Envelope Assembly
Pathways	Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin
GWAS	Antipsychotic drug-induced weight gain in schizophrenia ( 31447353 ) Perceived intensity of neohesperidin dihydrochalcone ( 31005972 ) Waist circumference adjusted for body mass index ( 28552196 )
Entrez ID	93099
HPRD ID	12387
Ensembl ID	ENSG00000161249
Uniprot IDs	A3EZ84 C9IYI1 C9J186 C9JCN1 E9PAQ7 M0R0A5 M0R3F8 Q6E0U4
PDB IDs	4F20
GO Terms Enriched among Interactors ?	Positive Regulation Of Response To Endoplasmic Reticulum Stress Positive Regulation Of ERAD Pathway Regulation Of Response To Endoplasmic Reticulum Stress Regulation Of ERAD Pathway Positive Regulation Of Proteolysis Positive Regulation Of Protein Catabolic Process Post-translational Protein Targeting To Endoplasmic Reticulum Membrane ERAD Pathway Positive Regulation Of Proteasomal Protein Catabolic Process Regulation Of Protein Catabolic Process Regulation Of Proteolysis TRC Complex Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Polyubiquitin Modification-dependent Protein Binding Regulation Of Cellular Response To Stress Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Catabolic Process Response To Endoplasmic Reticulum Stress Protein Targeting To Membrane Positive Regulation Of Protein Metabolic Process Identical Protein Binding Tail-anchored Membrane Protein Insertion Into ER Membrane Proteasomal Protein Catabolic Process Molecular Adaptor Activity Protein Catabolic Process Establishment Of Protein Localization To Membrane Protein Targeting Protein Insertion Into ER Membrane Proteolysis Involved In Protein Catabolic Process Regulation Of Protein Metabolic Process Hsp70 Protein Binding Cytoplasmic Vesicle Establishment Of Protein Localization To Organelle Negative Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Catabolic Process Protein Insertion Into Membrane Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Regulation Of Receptor Internalization Macromolecule Catabolic Process Negative Regulation Of Store-operated Calcium Channel Activity Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Autophagosome Autophagosome Assembly