STK17A

Description		serine/threonine kinase 17a
Image
GO Annotations	Cellular Component	Nucleus Plasma Membrane Nuclear Speck
	Molecular Function	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity ATP Binding Kinase Activity Transferase Activity Protein Serine Kinase Activity
	Biological Process	Protein Phosphorylation Apoptotic Process Intracellular Signal Transduction Positive Regulation Of Apoptotic Process Positive Regulation Of Fibroblast Apoptotic Process Regulation Of Reactive Oxygen Species Metabolic Process
Pathways
Drugs		Fostamatinib
Diseases
GWAS		HDL cholesterol levels in HIV infection ( 33109212) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494)
Interacting Genes		1 interacting genes: TRAF6
Entrez ID		9263
HPRD ID		05288
Ensembl ID		ENSG00000164543
Uniprot IDs		Q9UEE5
PDB IDs		7QUE 7QUF
Enriched GO Terms of Interacting Partners?		Bone Resorption Positive Regulation Of T Cell Cytokine Production MyD88-dependent Toll-like Receptor Signaling Pathway Ubiquitin-ubiquitin Ligase Activity CD40 Signaling Pathway Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway Regulation Of Receptor Localization To Synapse Regulation Of Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Non-canonical NF-kappaB Signal Transduction Bone Remodeling Myeloid Dendritic Cell Differentiation Interleukin-1-mediated Signaling Pathway Positive Regulation Of Osteoclast Differentiation Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II CD40 Receptor Complex Positive Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell Regulation Of Protein Localization To Synapse Stimulatory C-type Lectin Receptor Signaling Pathway Positive Regulation Of JUN Kinase Activity Ubiquitin Conjugating Enzyme Binding MyD88-independent Toll-like Receptor Signaling Pathway Endolysosomal Toll-like Receptor Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway Tumor Necrosis Factor Receptor Binding Interleukin-17A-mediated Signaling Pathway Protein Branched Polyubiquitination Protein Kinase B Binding Interleukin-33-mediated Signaling Pathway Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Myeloid Dendritic Cell Activation Toll-like Receptor 3 Signaling Pathway Cellular Response To Lectin Regulation Of Lipopolysaccharide-mediated Signaling Pathway T-helper 1 Type Immune Response Fc-epsilon Receptor Signaling Pathway Interleukin-17-mediated Signaling Pathway Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Dendritic Cell Differentiation Positive Regulation Of Interleukin-2 Production Positive Regulation Of MAP Kinase Activity Activation Of Protein Kinase Activity Antigen Processing And Presentation Of Exogenous Peptide Antigen Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell Regulation Of T Cell Cytokine Production Lipopolysaccharide-mediated Signaling Pathway Toll-like Receptor 4 Signaling Pathway Positive Regulation Of Interleukin-12 Production Cell Surface Toll-like Receptor Signaling Pathway Osteoclast Differentiation
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