STK17B

Description		serine/threonine kinase 17b
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Endoplasmic Reticulum-Golgi Intermediate Compartment Plasma Membrane Actin Cytoskeleton Membrane Flemming Body
	Molecular Function	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity ATP Binding Kinase Activity Transferase Activity Protein Serine Kinase Activity
	Biological Process	Protein Phosphorylation Apoptotic Process Programmed Cell Death Intracellular Signal Transduction Positive Regulation Of Apoptotic Process Protein Autophosphorylation Positive Regulation Of Fibroblast Apoptotic Process
Pathways
Drugs		Quercetin Fostamatinib
Diseases
GWAS		Eosinophil count ( 32888494) Eosinophil percentage of white cells ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494)
Novel Interacting Genes		1 novel interacting genes: DNAH7
Interacting Genes		3 interacting genes: APP CHP1 RPS24
Entrez ID		9262
HPRD ID		05289
Ensembl ID		ENSG00000081320
Uniprot IDs		O94768 Q53QE7
PDB IDs		3LM0 3LM5 6QF4 6Y6F 6Y6H 6ZJF 7AKG 7Q7C 7Q7D 7Q7E
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Negative Regulation Of Protein Localization To Nucleus Membrane Raft Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Regulation Of Response To Calcium Ion Amylin Binding Endosome To Plasma Membrane Transport Vesicle Negative Regulation Of Protein Localization Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Regulation Of Calcium-mediated Signaling Lipoprotein Particle Regulation Of Protein Localization To Nucleus Microtubule-based Process Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Negative Regulation Of Protein Autophosphorylation Positive Regulation Of Protein Glycosylation Transporter Complex Negative Regulation Of Phosphatase Activity Positive Regulation Of Sodium:proton Antiporter Activity Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Growth Factor Receptor Binding Main Axon Inner Dynein Arm Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Regulation Of Monoatomic Cation Transmembrane Transport Positive Regulation Of Protein Transport Negative Regulation Of Dephosphorylation Axon Choice Point Recognition Homeostatic Process Regulation Of Protein Glycosylation Positive Regulation Of Sodium Ion Transmembrane Transporter Activity
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