DSEL

Description		dermatan sulfate epimerase like
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Membrane
	Molecular Function	Sulfotransferase Activity Isomerase Activity Chondroitin-glucuronate 5-epimerase Activity
	Biological Process	Dermatan Sulfate Proteoglycan Biosynthetic Process Chondroitin Sulfate Proteoglycan Metabolic Process Dermatan Sulfate Proteoglycan Metabolic Process
Pathways		DS-GAG biosynthesis
Drugs
Diseases
GWAS		Blood pressure (smoking interaction) ( 25189868) Chronotype ( 30696823) Cognitive performance ( 19734545) Intraocular pressure ( 29617998) Major depressive disorder ( 20125088) Metabolite levels ( 23823483) Night sleep phenotypes ( 27126917) Non-response to selective serotonin reuptake inhibitors and depression ( 27622933) Spatial memory ( 31596458)
Interacting Genes		1 interacting genes: SPP1
Entrez ID		92126
HPRD ID		10720
Ensembl ID		ENSG00000171451
Uniprot IDs		Q8IZU8
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Positive Regulation Of Estradiol Secretion Regulation Of Estradiol Secretion Positive Regulation Of Bone Resorption Response To Macrophage Colony-stimulating Factor Hormone Catabolic Process Androgen Catabolic Process Negative Regulation Of Collateral Sprouting Negative Regulation Of Axon Regeneration Cellular Response To Testosterone Stimulus Negative Regulation Of Neuron Projection Regeneration Response To 2,3,7,8-tetrachlorodibenzodioxine Regulation Of Collateral Sprouting Decidualization Regulation Of Neuron Projection Regeneration Response To Vitamin D Extracellular Matrix Binding Regulation Of Axon Regeneration Small Molecule Binding Androgen Metabolic Process Steroid Catabolic Process Regulation Of Bone Resorption Embryo Implantation Regulation Of Bone Remodeling Response To Testosterone Negative Regulation Of Axonogenesis Response To Vitamin Regulation Of Tissue Remodeling Positive Regulation Of Lipid Transport Negative Regulation Of Developmental Growth Biomineral Tissue Development Ossification Osteoblast Differentiation Negative Regulation Of Nervous System Development Regulation Of Axonogenesis Integrin Binding Response To Nutrient Regulation Of Lipid Transport Negative Regulation Of Neurogenesis Negative Regulation Of Neuron Projection Development Positive Regulation Of Hormone Secretion Negative Regulation Of Cell Growth Vesicle Regulation Of Response To Wounding Negative Regulation Of Cell Projection Organization Hormone Metabolic Process Cytokine Activity Response To Ketone Response To Steroid Hormone Negative Regulation Of Growth
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