TIMD4

Description		T cell immunoglobulin and mucin domain containing 4
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GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Membrane
	Molecular Function	Phosphatidylserine Binding
	Biological Process	Apoptotic Cell Clearance Cytoskeletal Rearrangement Involved In Phagocytosis, Engulfment
Pathways
Drugs
Diseases
GWAS		Apolipoprotein B levels ( 32203549) Cholesterol, total ( 20686565 24097068 25961943) Hypertriglyceridemia ( 23505323) LDL cholesterol ( 20686565 19060906 24097068 25961943) LDL cholesterol levels ( 32203549 28334899) LDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535) LDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535) Low density lipoprotein cholesterol levels ( 33339817 29403010) Medication use (HMG CoA reductase inhibitors) ( 31015401) Platelet count ( 32888494) Plateletcrit ( 27863252 32888494) Total cholesterol levels ( 28334899 29403010 33339817) Triglyceride levels ( 33339817 32203549 32154731 28334899) Triglycerides ( 25961943 24097068 20686565)
Interacting Genes		2 interacting genes: CFTR FN1
Entrez ID		91937
HPRD ID		15508
Ensembl ID		ENSG00000145850
Uniprot IDs		Q96H15
PDB IDs		5DZN 5F7F 5F7H
Enriched GO Terms of Interacting Partners?		Apical Plasma Membrane Positive Regulation Of Anion Channel Activity Positive Regulation Of Enamel Mineralization Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Positive Regulation Of Monoatomic Anion Transport Negative Regulation Of Monocyte Activation Calcium-independent Cell-matrix Adhesion Positive Regulation Of Substrate-dependent Cell Migration, Cell Attachment To Substrate Transepithelial Water Transport Positive Regulation Of Tooth Mineralization Chloride Channel Inhibitor Activity Chloride Channel Regulator Activity Regulation Of Enamel Mineralization Membrane Hyperpolarization Neural Crest Cell Migration Involved In Autonomic Nervous System Development Bicarbonate Transmembrane Transporter Activity Intracellular PH Elevation Fibrinogen Complex Amelogenesis Peptidase Activator Activity Blood Coagulation, Fibrin Clot Formation ATPase-coupled Inorganic Anion Transmembrane Transporter Activity Integrin Activation Regulation Of Monoatomic Anion Transport Epithelial Fluid Transport Negative Regulation Of Transforming Growth Factor Beta Production Proteoglycan Binding Golgi-associated Vesicle Membrane Cellular Response To Forskolin Response To Forskolin Chloride Transmembrane Transporter Activity Anatomical Structure Formation Involved In Morphogenesis Sperm Capacitation Protein Activation Cascade Bicarbonate Transport Water Transport Multicellular Organismal-level Water Homeostasis Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of Ion Transmembrane Transporter Activity Vesicle Docking Involved In Exocytosis Cholesterol Biosynthetic Process 14-3-3 Protein Binding Fluid Transport Positive Regulation Of Transporter Activity ABC-type Transporter Activity Transepithelial Transport Acute-phase Response Endodermal Cell Differentiation
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