CENPL

Description		centromere protein L
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GO Annotations	Cellular Component	Chromosome, Centromeric Region Inner Kinetochore Nucleus Nucleoplasm Chromosome Cytosol
	Molecular Function	Protein Binding
	Biological Process	Chromosome Segregation
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS
Interacting Genes		2 interacting genes: FAM9B JMJD6
Entrez ID		91687
HPRD ID		15909
Ensembl ID		ENSG00000120334
Uniprot IDs		Q8N0S6
PDB IDs		7PKN 7QOO 7R5S 7R5V 7XHN 7XHO 7YWX 7YYH
Enriched GO Terms of Interacting Partners?		Histone H4R3 Demethylase Activity Peptidyl-lysine Hydroxylation To 5-hydroxy-L-lysine Peptidyl-lysine 5-dioxygenase Activity Histone H3R2 Demethylase Activity Oxidative RNA Demethylation Negative Regulation Of Protein Homooligomerization Oxidative RNA Demethylase Activity Protein Demethylase Activity P-TEFb Complex Binding Negative Regulation Of Protein Oligomerization Recognition Of Apoptotic Cell Oxidative Demethylation Peptidyl-lysine Hydroxylation Demethylation Transcription Regulator Activator Activity Phagocytosis, Recognition Protein Hydroxylation Histone Demethylase Activity Cell Development Apoptotic Cell Clearance Synaptonemal Complex Erythrocyte Development Sprouting Angiogenesis T Cell Differentiation In Thymus Single-stranded RNA Binding Macrophage Activation Myeloid Cell Development Dioxygenase Activity Retina Development In Camera-type Eye
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