DGKI

Gene Name		diacylglycerol kinase, iota
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Plasma Membrane Guanyl-nucleotide Exchange Factor Complex Dendritic Spine Synapse Perinuclear Region Of Cytoplasm
	Molecular Function	NAD+ Kinase Activity Diacylglycerol Kinase Activity GTPase Inhibitor Activity Protein Binding ATP Binding Ras GTPase Binding Metal Ion Binding
	Biological Process	Protein Kinase C-activating G-protein Coupled Receptor Signaling Pathway Blood Coagulation Phosphorylation Platelet Activation Regulation Of Rap GTPase Activity Intracellular Signal Transduction Negative Regulation Of Catalytic Activity Positive Regulation Of Ras Protein Signal Transduction
Pathways		G alpha (q) signalling events G alpha (q) signalling events Signaling by GPCR GPCR downstream signaling Gastrin-CREB signalling pathway via PKC and MAPK Platelet activation, signaling and aggregation Effects of PIP2 hydrolysis
Drugs
Diseases
GWAS		AIDS progression ( 21502085)
Protein-protein Interactions		1 interactors: VHL
Entrez ID		9162
HPRD ID		07238
Ensembl ID		ENSG00000157680
Uniprot IDs		E9PFX6 O75912
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Protein Stabilization Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Cellular Response To Oxygen Levels
Tagcloud ?		actionable adamts18 col1a1 d816 epha4 epha7 g12 g13 gna11 gnaq gucy2c k642 kalrn l576 melanomas mined ngs nras pik3r4 ppp6c prkaa2 q209 q61 stk31 taf1l trpm6 v559 v600 w557