RSAD2

Description		radical S-adenosyl methionine domain containing 2
Image		No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Mitochondrion Mitochondrial Outer Membrane Mitochondrial Inner Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Lipid Droplet Membrane
	Molecular Function	Catalytic Activity Protein Binding Lyase Activity Metal Ion Binding Iron-sulfur Cluster Binding 4 Iron, 4 Sulfur Cluster Binding
	Biological Process	Immune System Process Response To Virus Positive Regulation Of Toll-like Receptor 7 Signaling Pathway Positive Regulation Of Toll-like Receptor 9 Signaling Pathway CD4-positive, Alpha-beta T Cell Activation CD4-positive, Alpha-beta T Cell Differentiation Negative Regulation Of Viral Genome Replication Innate Immune Response Negative Regulation Of Protein Secretion Positive Regulation Of Immune Response Defense Response To Virus Positive Regulation Of T-helper 2 Cell Cytokine Production
Pathways		Interferon alpha/beta signaling
Drugs
Diseases
GWAS		Severe autoimmune type 2 diabetes ( 34737425)
Interacting Genes		6 interacting genes: APOC1 APOC2 APOC4 RHBDD2 TRAF6 UBE4A
Entrez ID		91543
HPRD ID		07423
Ensembl ID		ENSG00000134321
Uniprot IDs		C9J674 Q8WXG1
PDB IDs
Enriched GO Terms of Interacting Partners?		High-density Lipoprotein Particle Very-low-density Lipoprotein Particle Acylglycerol Homeostasis Triglyceride Homeostasis Negative Regulation Of Very-low-density Lipoprotein Particle Clearance Chylomicron Remnant Clearance Triglyceride-rich Lipoprotein Particle Clearance Regulation Of Phospholipid Catabolic Process Lipase Inhibitor Activity Chylomicron Phospholipid Efflux Ubiquitin-ubiquitin Ligase Activity Negative Regulation Of Lipoprotein Particle Clearance Lipid Homeostasis Negative Regulation Of Cholesterol Transport Plasma Lipoprotein Particle Clearance Cholesterol Efflux Negative Regulation Of Receptor-mediated Endocytosis Lipoprotein Metabolic Process Regulation Of Phospholipid Metabolic Process Plasma Lipoprotein Particle Remodeling Protein-containing Complex Remodeling Negative Regulation Of Lipid Transport Regulation Of Triglyceride Metabolic Process Regulation Of Fatty Acid Biosynthetic Process Lipid Transport Regulation Of Lipid Catabolic Process Regulation Of Cholesterol Transport Cholesterol Transport Negative Regulation Of Endocytosis Sterol Transport Negative Regulation Of Phosphatidylcholine Catabolic Process Phospholipid Transport Homeostatic Process ERAD Pathway Regulation Of Fatty Acid Metabolic Process Negative Regulation Of Lipid Metabolic Process Regulation Of Phosphorus Metabolic Process Positive Regulation Of Very-low-density Lipoprotein Particle Remodeling Protein Metabolic Process Regulation Of Receptor-mediated Endocytosis Regulation Of Ketone Metabolic Process Protein Catabolic Process Regulation Of Lipid Transport Organophosphate Ester Transport Regulation Of Phosphatidylcholine Catabolic Process Positive Regulation Of Phospholipid Catabolic Process Lipoprotein Lipase Activator Activity Organic Hydroxy Compound Transport Chylomicron Remodeling
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