SLC28A2

Description		solute carrier family 28 member 2
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Vesicle Membrane Membrane Apicolateral Plasma Membrane Coated Vesicle Brush Border Membrane
	Molecular Function	Neurotransmitter Transmembrane Transporter Activity Nucleoside Transmembrane Transporter Activity Purine Nucleobase Transmembrane Transporter Activity Nucleoside:sodium Symporter Activity Purine Nucleoside Transmembrane Transporter Activity Uridine Transmembrane Transporter Activity Pyrimidine- And Adenosine-specific:sodium Symporter Activity Azole Transmembrane Transporter Activity
	Biological Process	Retina Homeostasis Nucleobase-containing Compound Metabolic Process Xenobiotic Metabolic Process Neurotransmitter Transport Xenobiotic Transmembrane Transport Pyrimidine Nucleobase Transport Purine Nucleoside Transmembrane Transport Uridine Transmembrane Transport Adenosine Transport Inosine Transport Azole Transmembrane Transport Pyrimidine-containing Compound Transmembrane Transport Transport Across Blood-brain Barrier Nucleoside Transmembrane Transport Purine Nucleobase Transmembrane Transport
Pathways		Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane Azathioprine ADME Ribavirin ADME
Drugs
Diseases
GWAS		Estimated glomerular filtration rate ( 31015462) Uric acid levels ( 22229870) Urinary metabolite levels in chronic kidney disease ( 31959995)
Novel Interacting Genes		3 novel interacting genes: IDE NCOA1 PLAT
Interacting Genes
Entrez ID		9153
HPRD ID		07069
Ensembl ID		ENSG00000137860
Uniprot IDs		O43868 Q2M2A7 Q53H72
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Proteolysis Beta-endorphin Binding Positive Regulation Of Transcription From RNA Polymerase II Promoter By Galactose Protein-containing Complex Binding Bradykinin Catabolic Process Ubiquitin Recycling Cytosolic Proteasome Complex Insulin Catabolic Process Insulin Binding Trans-synaptic Signaling By BDNF, Modulating Synaptic Transmission Prevention Of Polyspermy Trans-synaptic Signaling By BDNF Serine Protease Inhibitor Complex Regulation Of Body Fluid Levels Negative Regulation Of Plasminogen Activation Cellular Response To Thyroglobulin Triiodothyronine Response To Thyroglobulin Triiodothyronine Regulation Of Thyroid Hormone Receptor Signaling Pathway Male Mating Behavior Labyrinthine Layer Morphogenesis Carbon Catabolite Regulation Of Transcription Positive Regulation Of Female Receptivity Amyloid-beta Clearance By Cellular Catabolic Process Regulation Of Female Receptivity Female Mating Behavior Regulation Of Proteolysis Positive Regulation Of Protein Binding Peptidase Activity Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Plasminogen Activation Negative Regulation Of Fibrinolysis Trans-synaptic Signaling, Modulating Synaptic Transmission Regulation Of Fertilization Peroxisome Proliferator Activated Receptor Signaling Pathway Progesterone Receptor Signaling Pathway Estrous Cycle Smooth Muscle Cell Migration Positive Regulation Of Adipose Tissue Development Hormone Catabolic Process Hypothalamus Development Insulin Metabolic Process Peptide Catabolic Process Regulation Of Fibrinolysis Regulation Of Plasminogen Activation Nuclear Retinoid X Receptor Binding Ovulation Cycle Nuclear Retinoic Acid Receptor Binding Regulation Of Biological Quality Negative Regulation Of Protein Metabolic Process Fibrinolysis
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