CD1E

Description		CD1e molecule
Image
GO Annotations	Cellular Component	Golgi Membrane Extracellular Space Nucleolus Lysosome Endosome Early Endosome Late Endosome Golgi Apparatus Plasma Membrane External Side Of Plasma Membrane Membrane Lysosomal Lumen
	Molecular Function	Lipid Binding Endogenous Lipid Antigen Binding Exogenous Lipid Antigen Binding Lipopeptide Binding
	Biological Process	Positive Regulation Of T Cell Mediated Cytotoxicity Adaptive Immune Response Immune System Process Immune Response Antigen Processing And Presentation, Endogenous Lipid Antigen Via MHC Class Ib Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib
Pathways
Drugs
Diseases
GWAS		QRS duration ( 27577874)
Interacting Genes		1 interacting genes: B2M
Entrez ID		913
HPRD ID		01781
Ensembl ID		ENSG00000158488
Uniprot IDs		A2RRL5 P15812
PDB IDs		3S6C
Enriched GO Terms of Interacting Partners?		Cellular Response To Iron(III) Ion Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class Ib Negative Regulation Of Forebrain Neuron Differentiation Regulation Of Forebrain Neuron Differentiation Response To Iron(III) Ion Antigen Processing And Presentation Of Exogenous Protein Antigen Via MHC Class Ib, TAP-dependent Negative Regulation Of Iron Ion Transport Cellular Response To Nicotine HFE-transferrin Receptor Complex Regulation Of Iron Ion Transport MHC Class I Protein Complex MHC Class I Peptide Loading Complex Cellular Response To Iron Ion Early Endosome Lumen Peptide Antigen Assembly With MHC Class I Protein Complex Transferrin Transport Positive Regulation Of Cellular Senescence Peptide Antigen Assembly With MHC Class II Protein Complex MHC Class II Protein Complex Positive Regulation Of T Cell Mediated Cytotoxicity Positive Regulation Of T Cell Cytokine Production Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Response To Iron Ion Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I MHC Class II Protein Complex Binding T Cell Mediated Cytotoxicity T Cell Mediated Immunity Antigen Processing And Presentation Of Endogenous Antigen Multicellular Organismal-level Iron Ion Homeostasis Amyloid Fibril Formation Protein Refolding Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Peptide Antigen Binding Negative Regulation Of Receptor-mediated Endocytosis Regulation Of T Cell Cytokine Production Antigen Processing And Presentation Of Exogenous Peptide Antigen Iron Ion Transport Regulation Of T Cell Mediated Cytotoxicity Response To Nicotine T Cell Differentiation In Thymus Antigen Processing And Presentation Of Exogenous Antigen Regulation Of Cellular Senescence Regulation Of Membrane Depolarization Regulation Of Erythrocyte Differentiation Positive Regulation Of Receptor-mediated Endocytosis Tertiary Granule Lumen ER To Golgi Transport Vesicle Membrane Specific Granule Lumen
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