BOD1

Description		biorientation of chromosomes in cell division 1
Image		No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Kinetochore Spindle Pole Outer Kinetochore Nucleoplasm Chromosome Cytoplasm Centrosome Cytoskeleton Spindle Microtubule Set1C/COMPASS Complex
	Molecular Function	Protein Phosphatase Inhibitor Activity Protein Binding Protein Phosphatase 2A Binding
	Biological Process	Mitotic Metaphase Chromosome Alignment Cell Division Protein Localization To Chromosome, Centromeric Region Mitotic Sister Chromatid Cohesion, Centromeric Mitotic Sister Chromatid Biorientation
Pathways		Formation of WDR5-containing histone-modifying complexes
Drugs
Diseases
GWAS		Chromosomal aberration frequency (chromatid type) ( 31586183) Height ( 20881960 25429064) Macular thickness ( 30535121) Prostate cancer ( 23535732) Refractive error ( 32231278) Urate levels in overweight individuals ( 25811787)
Interacting Genes		2 interacting genes: APP PLEKHF2
Entrez ID		91272
HPRD ID		13309
Ensembl ID		ENSG00000145919
Uniprot IDs		Q96IK1
PDB IDs
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Response To Calcium Ion Early Endosome Membrane Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Early Endosome Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Axon Choice Point Recognition Heparan Sulfate Binding Signaling Receptor Activator Activity Peptidase Activator Activity Cellular Response To Manganese Ion Negative Regulation Of Blood Circulation Regulation Of Superoxide Anion Generation Collateral Sprouting Heparan Sulfate Proteoglycan Binding Acetylcholine Receptor Binding Golgi-associated Vesicle Insulin Receptor Binding Apolipoprotein Binding Response To Lead Ion Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel High-density Lipoprotein Particle Very-low-density Lipoprotein Particle
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