FMNL3

Description		formin like 3
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Membrane
	Molecular Function	Actin Binding Protein Binding Small GTPase Binding GTPase Activating Protein Binding Actin Filament Binding
	Biological Process	Angiogenesis Cytoskeleton Organization Regulation Of Cell Shape Cell Migration Regulation Of Cell Morphogenesis Actin Cytoskeleton Organization Cortical Actin Cytoskeleton Organization Filopodium Assembly
Pathways		RHO GTPases Activate Formins RHOA GTPase cycle RHOC GTPase cycle CDC42 GTPase cycle RHOJ GTPase cycle
Drugs
Diseases
GWAS
Interacting Genes		3 interacting genes: APP NUDT1 PRPF40A
Entrez ID		91010
HPRD ID		17007
Ensembl ID		ENSG00000161791
Uniprot IDs		Q8IVF7
PDB IDs
Enriched GO Terms of Interacting Partners?		Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway 2-hydroxy-dATP Hydrolase Activity 2-hydroxy-ATP Hydrolase Activity O6-methyl-dGTP Hydrolase Activity DATP Diphosphatase Activity N6-methyl-(d)ATP Hydrolase Activity Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization 8-oxo-7,8-dihydroguanosine Triphosphate Pyrophosphatase Activity ATP Diphosphatase Activity 8-oxo-7,8-dihydrodeoxyguanosine Triphosphate Pyrophosphatase Activity Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Growth Factor Receptor Binding Main Axon Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Axon Choice Point Recognition Purine Nucleoside Catabolic Process DNA Protection Heparan Sulfate Binding Signaling Receptor Activator Activity Peptidase Activator Activity Cellular Response To Manganese Ion 5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] Hydrolase Activity Antifungal Humoral Response Nuclear Envelope Lumen Hydrolase Activity, Acting On Acid Anhydrides, In Phosphorus-containing Anhydrides
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