MAP3K6

Gene Name		mitogen-activated protein kinase kinase kinase 6
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm
	Molecular Function	Magnesium Ion Binding MAP Kinase Kinase Kinase Activity ATP Binding
	Biological Process	Activation Of MAPKK Activity Protein Phosphorylation Signal Transduction Activation Of JUN Kinase Activity
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		1 interactors: MAP3K5
Entrez ID		9064
HPRD ID		05126
Ensembl ID		ENSG00000142733
Uniprot IDs		O95382
PDB IDs
Enriched GO Terms of Interacting Partners?		Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress Cellular Response To Reactive Nitrogen Species Response To Ischemia Activation Of JUN Kinase Activity Programmed Necrotic Cell Death Necrotic Cell Death Cellular Response To Hydrogen Peroxide Activation Of MAPKK Activity Positive Regulation Of JUN Kinase Activity Positive Regulation Of Neuron Death Regulation Of JUN Kinase Activity JNK Cascade Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Cellular Response To Reactive Oxygen Species Zymogen Activation Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of JNK Cascade Positive Regulation Of Cysteine-type Endopeptidase Activity Response To Hydrogen Peroxide Positive Regulation Of Endopeptidase Activity Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Activation Of MAPK Activity Positive Regulation Of Peptidase Activity Regulation Of JNK Cascade Regulation Of Stress-activated MAPK Cascade Intrinsic Apoptotic Signaling Pathway Response To Reactive Oxygen Species Cellular Response To Oxidative Stress Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Cysteine-type Endopeptidase Activity Positive Regulation Of MAP Kinase Activity MAPK Cascade Protein Processing Activation Of Protein Kinase Activity Positive Regulation Of Protein Serine/threonine Kinase Activity Signal Transduction By Phosphorylation Regulation Of MAP Kinase Activity Regulation Of Neuron Death Positive Regulation Of Proteolysis Apoptotic Signaling Pathway Regulation Of Endopeptidase Activity Regulation Of Peptidase Activity Response To Oxidative Stress Positive Regulation Of MAPK Cascade Positive Regulation Of Protein Kinase Activity Response To Inorganic Substance
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