MLIP

Description		muscular LMNA interacting protein
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Cytoplasm Cytosol Plasma Membrane Membrane PML Body Nuclear Lumen Sarcolemma
	Molecular Function	Transcription Corepressor Activity Protein Binding Lamin Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Negative Regulation Of Cardiac Muscle Hypertrophy Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Cardiac Muscle Hypertrophy In Response To Stress
Pathways
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 33547301) Attention deficit hyperactivity disorder ( 29325848) Attention deficit hyperactivity disorder (hyperactivity-impulsivity symptoms) ( 32595297) Body size at age 10 ( 32376654) Creatinine levels ( 29403010) Gamma glutamyl transferase levels ( 29403010 33339817) Height ( 28552196) Liver enzyme levels (alanine transaminase) ( 33972514) Liver enzyme levels (gamma-glutamyl transferase) ( 22001757) Pulse pressure ( 27841878 30578418) Serum alkaline phosphatase levels ( 33547301) Systolic blood pressure ( 27841878) Urinary sodium excretion ( 31409800)
Interacting Genes		4 interacting genes: ABLIM2 LMNA MAPK9 REL
Entrez ID		90523
HPRD ID		12853
Ensembl ID		ENSG00000146147
Uniprot IDs		Q5VWP3
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Senescence Establishment Or Maintenance Of Microtubule Cytoskeleton Polarity Lamin Filament DNA Double-strand Break Attachment To Nuclear Envelope Nuclear Pore Localization Negative Regulation Of Gene Expression Structural Constituent Of Nuclear Lamina JUN Kinase Activity Protein Localization To Tricellular Tight Junction NF-kappaB Complex Nuclear Speck Nuclear Lamina Regulation Of Apoptotic Signaling Pathway Ventricular Cardiac Muscle Cell Development Protein Localization To Nuclear Envelope Negative Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Negative Regulation Of Mesenchymal Cell Proliferation Positive Regulation Of Podosome Assembly Regulation Of Podosome Assembly Inflammatory Response To Wounding MAP Kinase Activity Negative Regulation Of Interferon-beta Production
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