TICRR

Gene Name		TOPBP1-interacting checkpoint and replication regulator
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm
	Molecular Function	Chromatin Binding Protein Binding
	Biological Process	Cell Cycle Checkpoint Formation Of Translation Preinitiation Complex DNA Replication DNA Repair Response To Ionizing Radiation Regulation Of DNA-dependent DNA Replication Initiation Mitotic DNA Replication Checkpoint
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		2 interactors: APP TOPBP1
Entrez ID		90381
HPRD ID		11357
Ensembl ID		ENSG00000140534
Uniprot IDs		Q7Z2Z1
PDB IDs
Enriched GO Terms of Interacting Partners?		Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Response To Radiation Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Neuron Remodeling Cellular Copper Ion Homeostasis Copper Ion Homeostasis Suckling Behavior Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Response To Abiotic Stimulus Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis Neuron Recognition RNA Polyadenylation Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Ionotropic Glutamate Receptor Signaling Pathway Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Axon Cargo Transport Mating Neuromuscular Junction Development Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Neuron Apoptotic Process Regulation Of Protein Tyrosine Kinase Activity Visual Learning Glutamate Receptor Signaling Pathway Visual Behavior Neuron Death Platelet Degranulation Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Neuromuscular Process Controlling Balance Synapse Assembly MRNA 3'-end Processing Regulation Of ERBB Signaling Pathway Associative Learning Developmental Cell Growth Regulation Of Synapse Structure Or Activity Feeding Behavior Regulation Of Multicellular Organism Growth RNA 3'-end Processing Cholesterol Metabolic Process Adult Locomotory Behavior Positive Regulation Of Mitotic Cell Cycle
Tagcloud ?		acts assembly cdc45 checkpoint cmg depletion firing gins holohelicase integrate interacting interacts interfering irrespective mcm mdm means mtbp origin ortholog preventing propose replication sld3 stimulating throughout topbp1 treslin yeast