KLHL13

Description		kelch like family member 13
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Cul3-RING Ubiquitin Ligase Complex
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Cullin Family Protein Binding
	Biological Process	Protein Ubiquitination Regulation Of Cytokinesis Cell Division
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Iron status biomarkers ( 19084217)
Interacting Genes		3 interacting genes: AURKB UBC UBE2D1
Entrez ID		90293
HPRD ID		06461
Ensembl ID		ENSG00000003096
Uniprot IDs		A0A0C4DG80 B7ZB44 Q96HC9 Q9P2N7
PDB IDs
Enriched GO Terms of Interacting Partners?		Post-translational Protein Modification Mitotic Sister Chromatid Biorientation Repair Of Mitotic Kinetochore Microtubule Attachment Defect Positive Regulation Of Lateral Attachment Of Mitotic Spindle Microtubules To Kinetochore Protein Modification Process Mitotic Cytokinesis Checkpoint Signaling Positive Regulation Of Mitotic Cytokinesis Positive Regulation Of Microtubule Depolymerization Sister Chromatid Biorientation Regulation Of Metaphase Plate Congression Spindle Midzone Assembly Regulation Of Attachment Of Mitotic Spindle Microtubules To Kinetochore Negative Regulation Of B Cell Apoptotic Process Positive Regulation Of Attachment Of Mitotic Spindle Microtubules To Kinetochore Mitotic Spindle Midzone Assembly Mitotic Spindle Midzone Positive Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint Negative Regulation Of Cytokinesis Chromocenter Regulation Of Mitotic Cytokinesis Positive Regulation Of Attachment Of Spindle Microtubules To Kinetochore Chromosome Passenger Complex Cleavage Furrow Formation Positive Regulation Of Mitotic Sister Chromatid Segregation Protein Localization To Kinetochore Protein Tag Activity Negative Regulation Of Cell Division Modification-dependent Protein Catabolic Process Positive Regulation Of Protein Polyubiquitination Negative Regulation Of CGAS/STING Signaling Pathway Condensed Chromosome, Centromeric Region Positive Regulation Of Protein Depolymerization Positive Regulation Of Cell Cycle Checkpoint Regulation Of B Cell Apoptotic Process Attachment Of Mitotic Spindle Microtubules To Kinetochore Protein Ubiquitination Regulation Of Attachment Of Spindle Microtubules To Kinetochore Positive Regulation Of Mitotic Sister Chromatid Separation Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint Midbody Abscission Proteolysis Involved In Protein Catabolic Process Protein Metabolic Process Protein Modification By Small Protein Conjugation Mitotic Cytokinetic Process Protein Serine/threonine/tyrosine Kinase Activity CGAS/STING Signaling Pathway Spindle Midzone Regulation Of Protein Polyubiquitination Positive Regulation Of Chromosome Segregation Negative Regulation Of Intracellular Signal Transduction
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