SYT8

Description		synaptotagmin 8
Image		No pdb structure
GO Annotations	Cellular Component	Acrosomal Vesicle Cytoplasm Plasma Membrane Membrane Axon Synaptic Vesicle Membrane Dense Core Granule Cytoplasmic Vesicle Vesicle Exocytic Vesicle
	Molecular Function	SNARE Binding Calcium-dependent Phospholipid Binding Calcium-dependent Protein Binding Calcium Ion Sensor Activity
	Biological Process	Acrosome Reaction Vesicle-mediated Transport Regulation Of Calcium Ion-dependent Exocytosis Calcium-dependent Activation Of Synaptic Vesicle Fusion Regulation Of Synaptic Vesicle Exocytosis
Pathways		Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Celiac disease ( 23936387) Logical memory (delayed recall) in mild cognitive impairment ( 29274321)
Interacting Genes		1 interacting genes: SYNCRIP
Entrez ID		90019
HPRD ID		09655
Ensembl ID		ENSG00000149043
Uniprot IDs		Q8NBV8
PDB IDs
Enriched GO Terms of Interacting Partners?		Chromosomal 5-methylcytosine DNA Demethylation Pathway MCRD-mediated MRNA Stability Complex MRNA Editing Complex GAIT Complex Histone Pre-mRNA 3'end Processing Complex CRD-mediated MRNA Stability Complex Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay CRD-mediated MRNA Stabilization Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Regulation Of Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay MRNA Modification Positive Regulation Of Cytoplasmic Translation Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay MRNA 5'-UTR Binding Regulation Of Cytoplasmic Translation MRNA Stabilization Cellular Response To Type II Interferon Negative Regulation Of MRNA Catabolic Process RNA Stabilization Catalytic Step 2 Spliceosome Response To Type II Interferon Negative Regulation Of RNA Catabolic Process Negative Regulation Of MRNA Metabolic Process Osteoblast Differentiation RNA Modification Positive Regulation Of Translation Spliceosomal Complex Regulation Of MRNA Stability Negative Regulation Of Translation RNA Splicing, Via Transesterification Reactions Regulation Of RNA Stability MRNA Splicing, Via Spliceosome
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