DPH6

Description		diphthamine biosynthesis 6
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol
	Molecular Function	Nucleotide Binding ATP Binding Ligase Activity Diphthine-ammonia Ligase Activity
	Biological Process	Protein Histidyl Modification To Diphthamide
Pathways		Synthesis of diphthamide-EEF2
Drugs
Diseases
GWAS		Fasting glucose ( 34074324) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Optic nerve measurement (cup-to-disc ratio) ( 28061514) Photic sneeze reflex ( 27182965) Restless legs syndrome ( 29029846)
Interacting Genes		1 interacting genes: SMARCB1
Entrez ID		89978
HPRD ID		14443
Ensembl ID		ENSG00000134146
Uniprot IDs		Q7L8W6
PDB IDs
Enriched GO Terms of Interacting Partners?		XY Body BBAF Complex Tat Protein Binding Brahma Complex Viral RNA Genome Replication Regulation Of Transcription Of Nucleolar Large RRNA By RNA Polymerase I RSC-type Complex Positive Regulation Of Transcription Of Nucleolar Large RRNA By RNA Polymerase I DNA Integration Positive Regulation Of Glucose Mediated Signaling Pathway Hepatocyte Differentiation RNA Polymerase I Core Promoter Sequence-specific DNA Binding NpBAF Complex Germ Cell Nucleus RNA Polymerase I Preinitiation Complex Assembly Regulation Of Glucose Mediated Signaling Pathway Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate NBAF Complex Host-mediated Activation Of Viral Transcription Nucleosome Disassembly Viral Genome Replication Regulation Of Nucleotide-excision Repair Nuclear Chromosome Blastocyst Hatching Blastocyst Development Positive Regulation Of Transcription By RNA Polymerase I SWI/SNF Complex Protein-DNA Complex Disassembly Host-mediated Perturbation Of Viral Transcription Regulation Of G0 To G1 Transition Host-mediated Activation Of Viral Process Nucleosomal DNA Binding Regulation Of Transcription By RNA Polymerase I Positive Regulation Of Myoblast Differentiation Positive Regulation Of Stem Cell Population Maintenance Transcription Initiation-coupled Chromatin Remodeling Positive Regulation Of Gene Expression, Epigenetic Transcription Preinitiation Complex Assembly Regulation Of Stem Cell Population Maintenance Host-mediated Perturbation Of Viral Process P53 Binding Regulation Of Myoblast Differentiation Regulation Of Mitotic Metaphase/anaphase Transition Positive Regulation Of Double-strand Break Repair Regulation Of Sister Chromatid Segregation Host-mediated Perturbation Of Symbiont Process Modulation Of Process Of Another Organism Positive Regulation Of T Cell Differentiation Regulation Of Chromosome Segregation Nuclear Matrix
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