FCHSD1

Description		FCH and double SH3 domains 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoplasmic Vesicle Neuromuscular Junction Cuticular Plate Protein-containing Complex Cell Projection Perikaryon Recycling Endosome
	Molecular Function	Lipid Binding
	Biological Process	Apoptotic Process Inflammatory Response Neuromuscular Synaptic Transmission Gene Expression Regulation Of Actin Filament Polymerization Positive Regulation Of Actin Filament Polymerization Response To Hydrogen Peroxide Import Into Nucleus Positive Regulation Of Cytoskeleton Organization Membrane Organization Response To Peptide Positive Regulation Of Supramolecular Fiber Organization
Pathways
Drugs
Diseases
GWAS		Refractive error ( 32231278)
Interacting Genes		2 interacting genes: ITSN2 LRRK2
Entrez ID		89848
HPRD ID		13320
Ensembl ID		ENSG00000197948
Uniprot IDs		Q86WN1
PDB IDs
Enriched GO Terms of Interacting Partners?		Clathrin-dependent Synaptic Vesicle Endocytosis Cellular Response To Curcumin Caveola Neck Negative Regulation Of Late Endosome To Lysosome Transport Amphisome Peroxidase Inhibitor Activity Negative Regulation Of Protein Processing Involved In Protein Targeting To Mitochondrion GTP-dependent Protein Kinase Activity Beta-catenin Destruction Complex Binding Wnt Signalosome Assembly Positive Regulation Of Protein Autoubiquitination Response To Curcumin Endocytosis Cytoplasmic Side Of Mitochondrial Outer Membrane Positive Regulation Of Dopamine Receptor Signaling Pathway Regulation Of Protein Autoubiquitination Positive Regulation Of Synaptic Vesicle Endocytosis Negative Regulation Of Protein Targeting To Mitochondrion Multivesicular Body, Internal Vesicle Regulation Of Kidney Size Regulation Of CAMKK-AMPK Signaling Cascade Regulation Of Branching Morphogenesis Of A Nerve Regulation Of Synaptic Vesicle Transport Tangential Migration From The Subventricular Zone To The Olfactory Bulb Positive Regulation Of Synaptic Vesicle Recycling Cellular Response To Dopamine Intracellular Distribution Of Mitochondria Regulation Of Retrograde Transport, Endosome To Golgi Positive Regulation Of Microglial Cell Activation Protein Localization To Endoplasmic Reticulum Exit Site Negative Regulation Of Establishment Of Protein Localization To Mitochondrion Response To Dopamine JUN Kinase Kinase Kinase Activity Regulation Of Neuron Maturation Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Cellular Response To Manganese Ion Import Into Cell Regulation Of ER To Golgi Vesicle-mediated Transport Regulation Of Dopamine Receptor Signaling Pathway Cellular Response To Ether Negative Regulation Of Excitatory Postsynaptic Potential Negative Regulation Of Autophagosome Assembly Co-receptor Binding Autolysosome Wnt Signalosome Intracellular Organelle Lumen Regulation Of SNARE Complex Assembly Locomotory Exploration Behavior Striatum Development Negative Regulation Of GTPase Activity
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