NAV3

Description		neuron navigator 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Outer Membrane Membrane Microtubule End
	Molecular Function	ATP Binding Microtubule Binding ATP Hydrolysis Activity
	Biological Process	Negative Regulation Of Microtubule Depolymerization Nervous System Development Neurogenesis Negative Regulation Of Cell Migration Positive Regulation Of Microtubule Polymerization Negative Regulation Of Interleukin-2 Production
Pathways
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Chloride levels ( 29403010) Chronotype ( 30696823) Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444) Diabetic kidney disease ( 26305897) Endometrial cancer ( 30093612) Endometrial cancer (endometrioid histology) ( 30093612) Gastroesophageal reflux disease ( 33608531) Heel bone mineral density ( 30598549 28869591) Height ( 31562340) HOMA-B (corrected for HOMA-IR) ( 30369944) Optic disc size ( 31809533) Plasma free amino acid levels ( 30659259) Platelet count ( 32888494) Plateletcrit ( 27863252 32888494) Response to bupropion and depression ( 27622933) Schizophrenia x sex interaction ( 34099189) Self-rated health ( 20707712) Sodium levels ( 29403010) Systemic mastocytosis ( 32752121) Urinary albumin-to-creatinine ratio ( 31630189)
Interacting Genes		3 interacting genes: APC LCOR PCAT1
Entrez ID		89795
HPRD ID		10114
Ensembl ID		ENSG00000067798
Uniprot IDs		A0A2R8YFX5 Q8IVL0
PDB IDs
Enriched GO Terms of Interacting Partners?		Wnt Signalosome Leading Edge Membrane Positive Regulation Of Pseudopodium Assembly Negative Regulation Of Microtubule Depolymerization Regulation Of Attachment Of Spindle Microtubules To Kinetochore Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Mitotic Spindle Assembly Checkpoint Signaling Protein Kinase Regulator Activity Heart Valve Development Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Negative Regulation Of Mitotic Metaphase/anaphase Transition Beta-catenin Destruction Complex Regulation Of Microtubule Depolymerization Negative Regulation Of Cyclin-dependent Protein Kinase Activity Catenin Complex Dynein Complex Binding Negative Regulation Of Protein Serine/threonine Kinase Activity Endocardial Cushion Morphogenesis Gamma-catenin Binding Microtubule Plus-end Binding Plasma Membrane Bounded Cell Projection Positive Regulation Of Protein Localization To Centrosome Regulation Of Protein Localization To Centrosome Cellular Response To Estradiol Stimulus Histone Methyltransferase Binding Ubiquitin-specific Protease Binding
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