HIST1H2BJ

Gene Name		histone cluster 1, H2bj
Image
Gene Ontology Annotations	Cellular Component	Nucleosome Extracellular Space Nucleus Nucleoplasm
	Molecular Function	DNA Binding Protein Heterodimerization Activity
	Biological Process	Innate Immune Response In Mucosa Chromatin Organization Nucleosome Assembly Antibacterial Humoral Response Defense Response To Gram-positive Bacterium
Pathways		RNA Polymerase I Chain Elongation RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription Mitotic Prophase Regulatory RNA pathways RNA Polymerase I Promoter Clearance Deposition of new CENPA-containing nucleosomes at the centromere Cellular Senescence Signaling by Wnt HATs acetylate histones M Phase Amyloids NoRC negatively regulates rRNA expression Packaging Of Telomere Ends Telomere Maintenance Nucleosome assembly RNF mutants show enhanced WNT signaling and proliferation XAV939 inhibits tankyrase, stabilizing AXIN DNA methylation Transcriptional regulation by small RNAs Meiotic recombination DNA Damage/Telomere Stress Induced Senescence Chromosome Maintenance Chromatin organization HDACs deacetylate histones misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling RNA Polymerase I Transcription formation of the beta-catenin:TCF transactivating complex Meiotic synapsis Epigenetic regulation of gene expression Senescence-Associated Secretory Phenotype (SASP) Negative epigenetic regulation of rRNA expression PRC2 methylates histones and DNA Cell Cycle, Mitotic Chromatin modifying enzymes Oxidative Stress Induced Senescence TCF dependent signaling in response to WNT RNA Polymerase I Promoter Opening SIRT1 negatively regulates rRNA Expression Signaling by WNT in cancer Condensation of Prophase Chromosomes
Drugs
Diseases
GWAS		Iron status biomarkers ( 19084217) Schizophrenia ( 19571809)
Protein-protein Interactions		3 interactors: JMJD6 LOX TLX3
Entrez ID		8970
HPRD ID		13657
Ensembl ID
Uniprot IDs		P06899
PDB IDs		3A6N 3AFA 3AN2 3AV1 3AV2 3AYW 3AZE 3AZF 3AZG 3AZH 3AZI 3AZJ 3AZK 3AZL 3AZM 3AZN 3W96 3W97 3W98 3W99
Enriched GO Terms of Interacting Partners?		Histone H3-R2 Demethylation Histone H4-R3 Demethylation Peptidyl-lysine Hydroxylation To 5-hydroxy-L-lysine Lung Development Respiratory Tube Development Respiratory System Development Elastic Fiber Assembly Recognition Of Apoptotic Cell Blood Vessel Development Vasculature Development Regulation Of Respiratory Gaseous Exchange By Neurological System Process Extracellular Matrix Assembly Phagocytosis, Recognition Regulation Of Respiratory System Process Tube Development Regulation Of Respiratory Gaseous Exchange Protein Hydroxylation Macrophage Activation Cardiovascular System Development Neuron Fate Specification Apoptotic Cell Clearance Histone Demethylation Protein Demethylation Erythrocyte Development System Development Respiratory Gaseous Exchange Sprouting Angiogenesis Collagen Fibril Organization Demethylation Multicellular Organismal Development Regulation Of MRNA Splicing, Via Spliceosome T Cell Differentiation In Thymus Anatomical Structure Development Neuron Fate Commitment
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