CDK5R2

Description		cyclin dependent kinase 5 regulatory subunit 2
Image		No pdb structure
GO Annotations	Cellular Component	Cyclin-dependent Protein Kinase Holoenzyme Complex Cytoplasm Plasma Membrane Membrane Protein Kinase 5 Complex Growth Cone Neuron Projection Presynapse
	Molecular Function	Actin Binding Lipid Binding Protein Kinase Binding Cyclin-dependent Protein Serine/threonine Kinase Activator Activity
	Biological Process	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Neuron Migration Axon Guidance Brain Development Cerebellum Development Superior Olivary Nucleus Maturation Hippocampus Development Layer Formation In Cerebral Cortex Positive Regulation Of Calcium Ion-dependent Exocytosis Regulation Of Cytoskeleton Organization
Pathways		NGF-stimulated transcription
Drugs
Diseases
GWAS		Male-pattern baldness ( 28196072) Obesity-related traits ( 23251661) QT interval ( 29213071) Refractive error ( 32231278)
Novel Interacting Genes		1 novel interacting genes: TUBA4A
Interacting Genes		4 interacting genes: ACTB ACTN1 CAMK2A CDK5
Entrez ID		8941
HPRD ID		04790
Ensembl ID		ENSG00000171450
Uniprot IDs		Q13319
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Protein Localization To Cell Periphery Regulation Of Protein Localization To Plasma Membrane Regulation Of Protein Localization To Membrane Cell Junction Assembly Synapse Regulation Of Synaptic Vesicle Recycling Cytoskeleton Organization Organelle Organization Platelet Aggregation Tau Protein Binding Actin Cytoskeleton Organization Brush Border Actin Filament-based Process Homotypic Cell-cell Adhesion Regulation Of Programmed Cell Death Regulation Of Apoptotic Process Regulation Of Cellular Localization Protein Localization To Cell Junction Actin Filament Cell Junction Organization Positive Regulation Of Norepinephrine Uptake Cellular Response To Cytochalasin B Peptidyl-threonine Autophosphorylation Regulation Of Neurotransmitter Secretion Negative Regulation Of Calcium Ion-dependent Exocytosis Of Neurotransmitter Positive Regulation Of Presynaptic Cytosolic Calcium Concentration Structural Constituent Of Cytoskeleton Nucleotide Binding Regulation Of Norepinephrine Uptake Structural Constituent Of Postsynapse Acetylcholine Receptor Activator Activity Axonogenesis Transporter Regulator Activity Platelet Morphogenesis Regulation Of Endocannabinoid Signaling Pathway ErbB-2 Class Receptor Binding Protein Kinase 5 Complex Negative Regulation Of Synaptic Plasticity Cerebellar Cortex Formation Positive Regulation Of Transport Regulation Of Transepithelial Transport Cell Adhesion Lamellipodium Cell-cell Junction Regulation Of Protein Localization Protein Localization To Adherens Junction Dense Body Cell Junction Regulation Of Synaptic Plasticity Calcium- And Calmodulin-dependent Protein Kinase Complex
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