SSH2

Description		slingshot protein phosphatase 2
Image
GO Annotations	Cellular Component	Acrosomal Vesicle Extracellular Space Cytoplasm Cytoskeleton Focal Adhesion Cytoplasmic Vesicle Anchoring Junction
	Molecular Function	Actin Binding Phosphoprotein Phosphatase Activity Protein Serine/threonine Phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Hydrolase Activity Phosphatase Activity
	Biological Process	Protein Dephosphorylation Spermatogenesis Actin Cytoskeleton Organization Cell Differentiation Negative Regulation Of Actin Filament Polymerization
Pathways
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823) Brain morphology (MOSTest) ( 32665545) Coffee consumption (cups per day) ( 25288136) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Heel bone mineral density ( 28869591) Hematocrit ( 32888494) Hemoglobin ( 32888494) Lung function (FEV1/FVC) ( 30804560) Lymphocyte count ( 32888494 27863252) Monocyte count ( 32888494 27863252) Monocyte percentage of white cells ( 32888494) Neutrophil count ( 32888494) Peak expiratory flow ( 30804560) Red blood cell count ( 32888494) White blood cell count ( 27863252 32888494)
Novel Interacting Genes		1 novel interacting genes: BIRC5
Interacting Genes		2 interacting genes: ACTB CFL1
Entrez ID		85464
HPRD ID		09487
Ensembl ID		ENSG00000141298
Uniprot IDs		A0A3B3ITS1 B4DK64 F5H527 Q76I76
PDB IDs		2NT2
Enriched GO Terms of Interacting Partners?		Regulation Of Sister Chromatid Segregation Regulation Of Chromosome Segregation Nuclear Matrix Regulation Of Mitotic Metaphase/anaphase Transition Positive Regulation Of Norepinephrine Uptake Cellular Response To Cytochalasin B Survivin Complex Mitotic Cytokinesis Cytoskeleton-dependent Cytokinesis Cofilin-actin Rod Negative Regulation Of Unidimensional Cell Growth Positive Regulation Of Establishment Of Cell Polarity Regulating Cell Shape Positive Regulation Of Barbed-end Actin Filament Capping Positive Regulation Of Protein Localization To Cell Leading Edge Cytoskeleton Organization Establishment Or Maintenance Of Cell Polarity Kinetochore Vesicle Regulation Of Organelle Organization Regulation Of Norepinephrine Uptake Negative Regulation Of Postsynaptic Density Organization Lamellipodium Cell-cell Junction Transporter Regulator Activity Regulation Of Protein Localization To Cell Leading Edge Regulation Of Programmed Cell Death Regulation Of Apoptotic Process Regulation Of Transepithelial Transport Regulation Of Chromosome Organization Cytoskeleton Positive Regulation Of Exit From Mitosis Cobalt Ion Binding Neural Fold Formation Actin Filament Fragmentation Actin Cytoskeleton Protein Localization To Adherens Junction Dense Body Interphase Microtubule Organizing Center Negative Regulation Of Dendritic Spine Maintenance Regulation Of Barbed-end Actin Filament Capping Morphogenesis Of A Polarized Epithelium Chromosome Passenger Complex Negative Regulation Of Lamellipodium Assembly Morphogenesis Of An Epithelium Regulation Of Mitotic Cell Cycle Phase Transition Structural Constituent Of Postsynaptic Actin Cytoskeleton Actin Cytoskeleton Organization Nitric-oxide Synthase Regulator Activity Positive Regulation Of Attachment Of Mitotic Spindle Microtubules To Kinetochore BBAF Complex
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