SLC22A16

Description		solute carrier family 22 member 16
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Membrane
	Molecular Function	Amine Transmembrane Transporter Activity Organic Cation Transmembrane Transporter Activity Carnitine Transmembrane Transporter Activity Spermidine Transmembrane Transporter Activity Transmembrane Transporter Activity
	Biological Process	Monoatomic Ion Transport Spermatogenesis Single Fertilization Organic Cation Transport Amine Transport Carnitine Transport Cell Differentiation Flagellated Sperm Motility Acid Secretion Transmembrane Transport Carnitine Transmembrane Transport Spermidine Transmembrane Transport
Pathways		SLC-mediated transport of organic cations
Drugs
Diseases
GWAS		Blood metabolite levels ( 26401656) Daytime sleep phenotypes ( 27126917) Glucose homeostasis traits ( 25524916) High light scatter reticulocyte count ( 27863252 32888494) High light scatter reticulocyte percentage of red cells ( 27863252 32888494) Immature fraction of reticulocytes ( 27863252 32888494) Mucinous adenocarcinoma in colorectal cancer ( 29942513) Red cell distribution width ( 32888494) Reticulocyte count ( 27863252 32888494) Reticulocyte fraction of red cells ( 32888494 27863252) Serum metabolite concentrations in chronic kidney disease ( 29545352) Serum metabolite levels ( 33031748) Zinc levels ( 26025379)
Interacting Genes		1 interacting genes: FOXP1
Entrez ID		85413
HPRD ID		12202
Ensembl ID		ENSG00000004809
Uniprot IDs		A0A0K0K1K9 Q86VW1
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Interleukin-21 Production Monocyte Activation Regulation Of Defense Response To Bacterium Positive Regulation Of Hydrogen Peroxide-mediated Programmed Cell Death Negative Regulation Of B Cell Apoptotic Process Osteoclast Development Negative Regulation Of Androgen Receptor Signaling Pathway Striatum Development Positive Regulation Of B Cell Receptor Signaling Pathway Endothelial Cell Activation Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production Regulation Of Monocyte Differentiation T Follicular Helper Cell Differentiation Core Promoter Sequence-specific DNA Binding Negative Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Regulation Of Macrophage Colony-stimulating Factor Production Regulation Of Endothelial Tube Morphogenesis Regulation Of B Cell Apoptotic Process Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Regulation Of B Cell Receptor Signaling Pathway Negative Regulation Of Cardiac Muscle Tissue Growth Nuclear Androgen Receptor Binding Positive Regulation Of Antigen Receptor-mediated Signaling Pathway Negative Regulation Of Striated Muscle Cell Differentiation T-helper Cell Differentiation Negative Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Negative Regulation Of Muscle Hypertrophy Response To Testosterone Negative Regulation Of Lymphocyte Apoptotic Process Negative Regulation Of Organ Growth Regulation Of Androgen Receptor Signaling Pathway Negative Regulation Of Cardiac Muscle Hypertrophy T Cell Differentiation Involved In Immune Response Osteoclast Differentiation CD4-positive, Alpha-beta T Cell Differentiation T Cell Activation Involved In Immune Response Regulation Of Heart Growth Macrophage Activation Alpha-beta T Cell Differentiation Forebrain Development Regulation Of Lymphocyte Apoptotic Process CD4-positive, Alpha-beta T Cell Activation Regulation Of Morphogenesis Of An Epithelium Myeloid Cell Development Negative Regulation Of Muscle Cell Differentiation Regulation Of Interleukin-12 Production Negative Regulation Of Leukocyte Apoptotic Process Regulation Of Cardiac Muscle Hypertrophy Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Positive Regulation Of Smooth Muscle Cell Proliferation
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