ABCC11

Description		ATP binding cassette subfamily C member 11
Image		No pdb structure
GO Annotations	Cellular Component	Vacuole Vacuolar Membrane Plasma Membrane Membrane Apical Plasma Membrane Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Extracellular Exosome
	Molecular Function	Nucleotide Binding ATP Binding Organic Anion Transmembrane Transporter Activity ABC-type Xenobiotic Transporter Activity Purine Nucleotide Transmembrane Transporter Activity ABC-type Glutathione S-conjugate Transporter Activity ABC-type Bile Acid Transporter Activity ATP Hydrolysis Activity ATPase-coupled Inorganic Anion Transmembrane Transporter Activity ABC-type Transporter Activity
	Biological Process	Lipid Transport Organic Anion Transport Bile Acid And Bile Salt Transport Purine Nucleotide Transport Xenobiotic Transport Transmembrane Transport Leukotriene Transport Monoatomic Anion Transmembrane Transport
Pathways		ABC-family proteins mediated transport
Drugs
Diseases
GWAS		Excessive sweating ( 29895819) Fasting plasma glucose ( 25187374)
Interacting Genes		1 interacting genes: CFTR
Entrez ID		85320
HPRD ID		06127
Ensembl ID		ENSG00000121270
Uniprot IDs		Q96J66
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Anion Channel Activity Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Positive Regulation Of Monoatomic Anion Transport Positive Regulation Of Enamel Mineralization Positive Regulation Of Tooth Mineralization Chloride Channel Inhibitor Activity Transepithelial Water Transport Chloride Channel Regulator Activity Regulation Of Enamel Mineralization Membrane Hyperpolarization Bicarbonate Transmembrane Transporter Activity Intracellular PH Elevation Amelogenesis ATPase-coupled Inorganic Anion Transmembrane Transporter Activity Regulation Of Monoatomic Anion Transport Epithelial Fluid Transport Golgi-associated Vesicle Membrane Cellular Response To Forskolin Response To Forskolin Chloride Transmembrane Transporter Activity Sperm Capacitation Bicarbonate Transport Water Transport Multicellular Organismal-level Water Homeostasis Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of Ion Transmembrane Transporter Activity Cholesterol Biosynthetic Process 14-3-3 Protein Binding Fluid Transport Transepithelial Transport Vesicle Docking Involved In Exocytosis Positive Regulation Of Transporter Activity ABC-type Transporter Activity Sterol Biosynthetic Process Chloride Channel Complex Positive Regulation Of Biomineral Tissue Development Cellular Response To CAMP Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Vesicle Docking Cholesterol Transport Clathrin-coated Endocytic Vesicle Membrane Odontogenesis Of Dentin-containing Tooth Chloride Channel Activity Multicellular Organismal-level Chemical Homeostasis Regulation Of Cellular PH Regulation Of Transmembrane Transporter Activity Membrane Docking Positive Regulation Of Exocytosis
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