FRMD5

Description		FERM domain containing 5
Image		No pdb structure
GO Annotations	Cellular Component	Cytoskeleton Adherens Junction Membrane Anchoring Junction
	Molecular Function	Integrin Binding Protein Binding Cytoskeletal Protein Binding Protein Kinase Binding
	Biological Process	Regulation Of Cell Migration Actomyosin Structure Organization Positive Regulation Of Cell Adhesion Negative Regulation Of Cell Motility
Pathways
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823) Hemoglobin levels ( 32327693) Lipoprotein phospholipase A2 activity in cardiovascular disease ( 28753643) Serum albumin levels ( 23022100) Serum alkaline phosphatase levels ( 33547301) Triglyceride levels ( 28334899) Triglycerides ( 20686565 24097068 25961943) Urinary tract infection frequency ( 28928442) Uterine fibroid number (single vs multiple) ( 30196971)
Novel Interacting Genes		2 novel interacting genes: CEP250 SC5D
Interacting Genes		1 interacting genes: NELFCD
Entrez ID		84978
HPRD ID		17493
Ensembl ID		ENSG00000171877
Uniprot IDs		A0A087WVP2 A8K1U8 B3KVN9 B5MC67 H0YKW6 Q7Z6J6
PDB IDs
Enriched GO Terms of Interacting Partners?		Cholesterol Biosynthetic Process Via Lathosterol Cholesterol Biosynthetic Process Via Desmosterol C-5 Sterol Desaturase Activity Delta7-sterol 5(6)-desaturase Activity Regulation Of Centriole-centriole Cohesion NELF Complex Positive Regulation Of Protein Localization To Centrosome Regulation Of Ferroptosis Negative Regulation Of Ferroptosis Spindle Pole Centrosome Centriole-centriole Cohesion Regulation Of Protein Localization To Centrosome Detection Of Light Stimulus Involved In Visual Perception Protein Localization To Centrosome Negative Regulation Of DNA-templated Transcription, Elongation Negative Regulation Of Transcription Elongation By RNA Polymerase II Cholesterol Biosynthetic Process Sterol Biosynthetic Process Protein Localization To Cytoskeleton Non-motile Cilium Assembly Photoreceptor Inner Segment Detection Of Light Stimulus
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