MPND

Description		MPN domain containing
Image		No pdb structure
GO Annotations	Cellular Component	BRCA1-A Complex BRISC Complex
	Molecular Function	Protein Binding Peptidase Activity Metallopeptidase Activity Hydrolase Activity Polyubiquitin Modification-dependent Protein Binding Metal Ion Binding Metal-dependent Deubiquitinase Activity
	Biological Process	Double-strand Break Repair Proteolysis
Pathways
Drugs
Diseases
GWAS		Asthma ( 32296059)
Interacting Genes		1 interacting genes: DLG4
Entrez ID		84954
HPRD ID		07873
Ensembl ID		ENSG00000008382
Uniprot IDs		Q8N594 W4VSR2
PDB IDs
Enriched GO Terms of Interacting Partners?		Cerebellar Mossy Fiber Synaptic Vesicle Maturation P2Y1 Nucleotide Receptor Binding Neuron Spine Positive Regulation Of Neuron Projection Arborization AMPA Glutamate Receptor Clustering Beta-1 Adrenergic Receptor Binding D1 Dopamine Receptor Binding Regulation Of Grooming Behavior NMDA Selective Glutamate Receptor Signaling Pathway Neuroligin Family Protein Binding Juxtaparanode Region Of Axon Neuron Projection Terminus Locomotory Exploration Behavior Cellular Response To Potassium Ion Regulation Of Neuron Projection Arborization Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Dendritic Spine Morphogenesis Acetylcholine Receptor Binding Neurotransmitter-gated Ion Channel Clustering Negative Regulation Of Receptor Internalization Response To Potassium Ion Vocalization Behavior Protein Localization To Postsynaptic Membrane Positive Regulation Of Excitatory Postsynaptic Potential Cortical Cytoskeleton Ionotropic Glutamate Receptor Binding AMPA Glutamate Receptor Complex Ionotropic Glutamate Receptor Signaling Pathway Dendritic Spine Organization Dendrite Cytoplasm Negative Regulation Of Receptor-mediated Endocytosis Regulation Of Long-term Neuronal Synaptic Plasticity Excitatory Synapse Protein Localization To Postsynapse Exploration Behavior Organelle Ligand-gated Ion Channel Signaling Pathway Neuron Projection Organization Postsynapse Organization Receptor Clustering Glutamate Receptor Signaling Pathway Neuromuscular Process Controlling Balance Modulation Of Excitatory Postsynaptic Potential Social Behavior Establishment Or Maintenance Of Apical/basal Cell Polarity Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Receptor Localization To Synapse Regulation Of Neuronal Synaptic Plasticity Protein Localization To Synapse
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