SERAC1

Description		serine active site containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Extracellular Matrix Mitochondrial Membrane Mitochondria-associated Endoplasmic Reticulum Membrane Contact Site
	Molecular Function
	Biological Process	Lipid Metabolic Process Phospholipid Biosynthetic Process Extracellular Matrix Organization Intracellular Cholesterol Transport Phosphatidylglycerol Acyl-chain Remodeling
Pathways
Drugs
Diseases
GWAS		Lipoprotein (a) - cholesterol levels ( 25575512) Lipoprotein (a) levels ( 26377243) Systemic sclerosis ( 29293537)
Interacting Genes		2 interacting genes: APP CFTR
Entrez ID		84947
HPRD ID		10223
Ensembl ID		ENSG00000122335
Uniprot IDs		Q96JX3
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein-folding Chaperone Binding Amyloid-beta Complex Response To Purine-containing Compound Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Recycling Endosome Amylin Binding Cell Maturation Positive Regulation Of Toll Signaling Pathway Cellular Response To CAMP Response To CAMP Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Early Endosome Membrane Developmental Maturation Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Positive Regulation Of Establishment Of Protein Localization Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Early Endosome Growth Cone Filopodium Regulation Of Monoatomic Ion Transmembrane Transport Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Positive Regulation Of Protein Transport Positive Regulation Of Anion Channel Activity Positive Regulation Of Monoatomic Anion Transport Response To Norepinephrine Intracellular Monoatomic Cation Homeostasis Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of Monoatomic Ion Transport Enzyme Binding Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Intracellular Monoatomic Ion Homeostasis Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Positive Regulation Of Enamel Mineralization Transepithelial Water Transport
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