ATG4C

Description		autophagy related 4C cysteine peptidase
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm
	Molecular Function	Cysteine-type Endopeptidase Activity Protein Binding Peptidase Activity Cysteine-type Peptidase Activity Hydrolase Activity Protein-phosphatidylethanolamide Deconjugating Activity
	Biological Process	Autophagosome Assembly Mitophagy Proteolysis Autophagy Protein Transport Protein Processing Piecemeal Microautophagy Of The Nucleus Aggrephagy Protein Delipidation
Pathways		Macroautophagy
Drugs
Diseases
GWAS		Body mass index ( 20966902) Calcium levels ( 25972035) Response to cyclophosphamide in systemic lupus erythematosus with lupus nephritis ( 26980576) Triglyceride levels ( 29615537) Triglycerides ( 18193044) Very long-chain saturated fatty acid levels (fatty acid 20:0) ( 25378659) Weight ( 20966902)
Interacting Genes		2 interacting genes: GABARAP MAP1LC3B
Entrez ID		84938
HPRD ID		07473
Ensembl ID		ENSG00000125703
Uniprot IDs		A0A384MTY5 Q96DT6
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Response To Nitrogen Starvation Phosphatidylethanolamine Binding Mitophagy Autophagosome Membrane Autophagosome Maturation Autophagy Of Mitochondrion Autophagosome Autophagosome Assembly Autophagosome Organization Phospholipid Binding Axoneme Protein-containing Complex Disassembly Macroautophagy Vacuole Organization Cellular Response To Starvation Response To Starvation Microtubule Binding Cellular Response To Nutrient Levels Endomembrane System Autophagy Ubiquitin Protein Ligase Binding Positive Regulation Of Protein K48-linked Ubiquitination Microtubule Regulation Of Protein K48-linked Ubiquitination Response To Nutrient Levels Ceramide Binding Organelle Assembly GABA Receptor Binding Regulation Of Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Positive Regulation Of Protein Polyubiquitination Smooth Endoplasmic Reticulum Cytoplasmic Vesicle Regulation Of Protein Localization To Synapse Regulation Of Protein Polyubiquitination Regulation Of Receptor Localization To Synapse Regulation Of Rac Protein Signal Transduction Microtubule Associated Complex Beta-tubulin Binding Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Organelle Membrane Sperm Midpiece Protein-containing Complex Organization Cytoskeleton Cellular Response To Stress Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process GABA-ergic Synapse Catabolic Process Positive Regulation Of Protein Ubiquitination Positive Regulation Of Proteasomal Protein Catabolic Process
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