UTP4

Description		UTP4 small subunit processome component
Image
GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm Chromosome Nucleolus 90S Preribosome Small-subunit Processome T-UTP Complex
	Molecular Function	RNA Binding Protein Binding
	Biological Process	Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Regulation Of DNA-templated Transcription RRNA Processing Maturation Of SSU-rRNA Ribosome Biogenesis Ribosomal Small Subunit Biogenesis
Pathways		rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases		Familial cholestasis, including: Progressive familial intrahepatic cholestasis (PFIC); Benign recurrent intrahepatic cholestasis (BRIC); Intrahepatic cholestasis of pregnancy (ICP); North American Indian childhood cirrhosis (NAIC)
GWAS
Novel Interacting Genes		1 novel interacting genes: TMEM97
Interacting Genes		2 interacting genes: APP PRNP
Entrez ID		84916
HPRD ID		08468
Ensembl ID		ENSG00000141076
Uniprot IDs		Q969X6
PDB IDs		7MQ8 7MQ9 7MQA
Enriched GO Terms of Interacting Partners?		Neuron Projection Maintenance Regulation Of Dendritic Spine Maintenance Negative Regulation Of Long-term Synaptic Potentiation Intracellular Copper Ion Homeostasis Copper Ion Homeostasis Positive Regulation Of Establishment Of Protein Localization Molecular Function Activator Activity Cellular Response To Copper Ion Response To Copper Ion Neuron Projection Organization Regulation Of Long-term Synaptic Potentiation Positive Regulation Of Protein Localization Regulation Of Amyloid Precursor Protein Catabolic Process Regulation Of Establishment Of Protein Localization Cellular Response To Amyloid-beta Positive Regulation Of Calcium-mediated Signaling Response To Amyloid-beta Positive Regulation Of Neuron Apoptotic Process Regulation Of Calcium-mediated Signaling Protein-folding Chaperone Binding Amyloid-beta Complex Growth Cone Lamellipodium Chemical Homeostasis Regulation Of Response To Calcium Ion Regulation Of Type II Interferon Production Amylin Binding Positive Regulation Of Toll Signaling Pathway Regulation Of Protein Localization Memory Type 8 Metabotropic Glutamate Receptor Binding Regulation Of Postsynapse Organization Regulation Of Calcium Ion Transmembrane Transport Cellular Response To Metal Ion Acetylcholine Receptor Activator Activity Lipoprotein Particle Positive Regulation Of Protein Import Protein Homooligomerization Membrane Raft PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Homeostatic Process Regulation Of Synaptic Plasticity Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Regulation Of Calcium Ion Transport Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization
Tagcloud ?