CEP89

Name	centrosomal protein 89
Structure	No pdb structure
Interactors	2 interactors: FXR1 PICK1
GO Annotations	Cellular Component	Spindle Pole Cytoplasm Mitochondrion Mitochondrial Intermembrane Space Centrosome Centriole Cytosol Cytoskeleton Cilium Nuclear Body Motile Cilium Ciliary Basal Body Synapse Ciliary Transition Fiber Non-motile Cilium
	Molecular Function	Protein Binding
	Biological Process	Mitochondrion Organization Chemical Synaptic Transmission Cell Projection Organization Mitochondrial Cytochrome C Oxidase Assembly Cilium Assembly Non-motile Cilium Assembly
Pathways	Anchoring of the basal body to the plasma membrane
GWAS	Chronic kidney disease ( 31152163 ) Estimated glomerular filtration rate ( 31152163 ) Estimated glomerular filtration rate in non-diabetics ( 31451708 ) L1-L4 bone mineral density x serum urate levels interaction ( 34046847 ) Longevity (age >90th survival percentile) ( 31413261 ) Serum metabolite levels ( 33031748 ) Urate levels ( 31578528 )
Entrez ID	84902
HPRD ID	08601
Ensembl ID	ENSG00000121289
Uniprot IDs	Q96ST8
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Regulation Of Synaptic Plasticity RNA Strand Annealing Activity Positive Regulation Of Long-term Neuronal Synaptic Plasticity Negative Regulation Of Long-term Synaptic Potentiation Localization Within Membrane Nuclear Pore Localization Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Neuron Projection Positive Regulation Of MiRNA-mediated Gene Silencing Intracellular Membraneless Organelle Nuclear Pore Complex Assembly Modulation Of Chemical Synaptic Transmission Negative Regulation Of Arp2/3 Complex-mediated Actin Nucleation Membrane Curvature Sensor Activity Negative Regulation Of Actin Nucleation Neuronal Ion Channel Clustering Dendritic Spine Maintenance Costamere Perinuclear Region Of Cytoplasm Ribonucleoprotein Granule Nuclear Pore Organization Arp2/3 Complex Binding Long-term Synaptic Depression Translation Regulator Activity Regulation Of Circadian Sleep/wake Cycle, Sleep Pore Complex Assembly Skeletal Muscle Organ Development MRNA 3'-UTR AU-rich Region Binding Dentate Gyrus Development Cell Development Synapse Regulation Of Circadian Sleep/wake Cycle Regulation Of Post-transcriptional Gene Silencing Regulation Of MiRNA-mediated Gene Silencing Regulation Of Long-term Neuronal Synaptic Plasticity Positive Regulation Of Rho Protein Signal Transduction Positive Regulation Of Receptor Internalization Regulation Of Arp2/3 Complex-mediated Actin Nucleation Monoamine Transport Dendritic Spine Organization Cytoplasmic Translational Initiation Regulation Of Actin Nucleation Negative Regulation Of Synaptic Transmission Ribonucleoprotein Complex Binding Presynaptic Modulation Of Chemical Synaptic Transmission Regulation Of Long-term Synaptic Potentiation Neuron Projection Organization Postsynapse Organization Molecular Condensate Scaffold Activity Cellular Response To Glucose Starvation