PLXDC2

Description		plexin domain containing 2
Image		No pdb structure
GO Annotations	Cellular Component	Membrane
	Molecular Function	Protein Binding
	Biological Process
Pathways
Drugs
Diseases
GWAS		Abdominal aortic calcification levels ( 31659325) Activated partial thromboplastin time ( 29403010) Blood protein levels ( 30072576) Bone mineral density (Ward's triangle area) ( 27397699) Bronchopulmonary dysplasia ( 23897914) Diabetic retinopathy ( 21310492) Hair color ( 26926045) Heel bone mineral density ( 28869591 30598549) Nicotine dependence and major depression (severity of comorbidity) ( 30287806) Non-HDL cholesterol levels ( 32902719) Photic sneeze reflex ( 27182965) Plasma factor V levels in venous thrombosis ( 31271701) Plasma factor V levels in venous thrombosis (conditioned on rs6027) ( 31271701) Proteinuria and chronic kidney disease ( 26420894) Prothrombin time ( 29403010) Pulse pressure ( 27841878 30578418) Retinal detachment or retinal break ( 31816047) Total cholesterol levels ( 32902719)
Interacting Genes		2 interacting genes: CLK1 ZBP1
Entrez ID		84898
HPRD ID		08440
Ensembl ID		ENSG00000120594
Uniprot IDs		Q6UX71
PDB IDs
Enriched GO Terms of Interacting Partners?		Left-handed Z-DNA Binding Execution Phase Of Necroptosis Double-stranded RNA Adenosine Deaminase Activity Regulation Of Interleukin-1-mediated Signaling Pathway Necroptotic Signaling Pathway Positive Regulation Of Necroptotic Process Positive Regulation Of Programmed Necrotic Cell Death Positive Regulation Of Type I Interferon-mediated Signaling Pathway Protein Serine/threonine/tyrosine Kinase Activity Regulation Of Necroptotic Process Non-membrane Spanning Protein Tyrosine Kinase Activity Regulation Of Type I Interferon-mediated Signaling Pathway Pyroptotic Inflammatory Response Regulation Of Programmed Necrotic Cell Death Defense Response To Fungus Positive Regulation Of Cytokine-mediated Signaling Pathway Response To Fungus Positive Regulation Of Response To Cytokine Stimulus Double-stranded RNA Binding Antiviral Innate Immune Response
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