GPR65

Description		G protein-coupled receptor 65
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GO Annotations	Cellular Component	Endosome Plasma Membrane Membrane Early Endosome Membrane Late Endosome Membrane
	Molecular Function	G Protein-coupled Receptor Activity
	Biological Process	Apoptotic Process Immune Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Response To Acidic PH Positive Regulation Of Interleukin-22 Production Positive Regulation Of T-helper Cell Differentiation Positive Regulation Of Stress Fiber Assembly Cellular Response To Acidic PH
Pathways		Class A/1 (Rhodopsin-like receptors) G alpha (q) signalling events
Drugs
Diseases
GWAS		Ankylosing spondylitis ( 23749187) California verbal learning test score ( 31596458) Cerebrospinal AB1-42 levels in normal cognition ( 29274321) Crohn's disease ( 21102463 28067908) Degraded stimulus continuous performance test score ( 31596458) Diastolic blood pressure night-to-day ratio in hypertension ( 29973135) Eosinophil percentage of white cells ( 32888494) Food antigen IgG levels ( 24962563) Inflammatory bowel disease ( 23128233 28067908) Multiple sclerosis ( 21833088) Parkinson's disease ( 32201043) Takayasu arteritis ( 25604533)
Novel Interacting Genes		2 novel interacting genes: CKB TRIP11
Interacting Genes
Entrez ID		8477
HPRD ID		07057
Ensembl ID		ENSG00000140030
Uniprot IDs		B5B0C2 Q8IYL9
PDB IDs		9BHL
Enriched GO Terms of Interacting Partners?		Futile Creatine Cycle Phosphocreatine Biosynthetic Process Creatine Kinase Activity Chondrocyte Differentiation Involved In Endochondral Bone Morphogenesis Vesicle Tethering To Golgi Golgi Ribbon Formation Transferase Activity, Transferring Phosphorus-containing Groups Acrosomal Membrane Vesicle Tethering Ventricular Septum Development Inner Ear Receptor Cell Stereocilium Organization Substantia Nigra Development Cardiac Septum Development Cis-Golgi Network Neural Nucleus Development Chondrocyte Differentiation
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