MYO18B

Description		myosin XVIIIB
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytoskeleton Myosin Complex Myosin II Complex Unconventional Myosin Complex Sarcomere Z Disc Filamentous Actin Myosin Filament
	Molecular Function	Nucleotide Binding Cytoskeletal Motor Activity Actin Binding ATP Binding Actin Filament Binding
	Biological Process	Vasculogenesis In Utero Embryonic Development Actomyosin Structure Organization Cardiac Muscle Cell Development
Pathways
Drugs
Diseases
GWAS		Amyotrophic lateral sclerosis (sporadic) ( 24529757) Atrial fibrillation ( 29892015 30061737) Brugada syndrome ( 35210625) Copper levels ( 26025379) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Gut microbiota (functional units) ( 27694959) Left ventricle wall thickness ( 33495596) Left ventricular mass to end-diastolic volume ratio ( 33495596) Mathematical ability in children with dyslexia ( 23423138) Schizophrenia, bipolar disorder and depression (combined) ( 20713499) Urate levels in lean individuals ( 25811787) Urinary calcium excretion ( 31993563)
Novel Interacting Genes		1 novel interacting genes: SMARCB1
Interacting Genes		4 interacting genes: ACTB PSMC5 SRPK2 TULP3
Entrez ID		84700
HPRD ID		09529
Ensembl ID		ENSG00000133454
Uniprot IDs		Q8IUG5
PDB IDs
Enriched GO Terms of Interacting Partners?		BBAF Complex Tat Protein Binding Brahma Complex NBAF Complex RSC-type Complex NpBAF Complex Regulation Of Nucleotide-excision Repair SWI/SNF Complex Regulation Of G0 To G1 Transition Nucleosomal DNA Binding Positive Regulation Of Myoblast Differentiation Positive Regulation Of Stem Cell Population Maintenance Regulation Of Stem Cell Population Maintenance Regulation Of Myoblast Differentiation Positive Regulation Of Double-strand Break Repair Regulation Of RNA Metabolic Process Regulation Of Mitotic Metaphase/anaphase Transition Positive Regulation Of Norepinephrine Uptake Cellular Response To Cytochalasin B Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Regulation Of Sister Chromatid Segregation Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Chromosome Segregation Blood Microparticle Positive Regulation Of T Cell Differentiation Nuclear Matrix Chromatin Remodeling Regulation Of Norepinephrine Uptake Nuclear Proteasome Complex Bronchus Morphogenesis Positive Regulation Of Lymphocyte Differentiation Positive Regulation Of DNA Repair Nucleoplasm Regulation Of Double-strand Break Repair Transporter Regulator Activity Regulation Of G1/S Transition Of Mitotic Cell Cycle Thyrotropin-releasing Hormone Receptor Binding Positive Regulation Of Glucose Mediated Signaling Pathway Germ Cell Nucleus Intraciliary Transport Particle A Binding Kinetochore Regulation Of Transepithelial Transport Regulation Of Cell Cycle G1/S Phase Transition Chromatin Organization Regulation Of T Cell Differentiation Regulation Of Glucose Mediated Signaling Pathway Nuclear Speck Organization Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning Positive Regulation Of Leukocyte Differentiation Protein Localization To Adherens Junction
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