COL25A1

Gene Name		collagen, type XXV, alpha 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Collagen Trimer Extracellular Space Endoplasmic Reticulum Lumen Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane
	Molecular Function	Beta-amyloid Binding Heparin Binding
	Biological Process	Extracellular Matrix Disassembly Extracellular Matrix Organization Collagen Catabolic Process
Pathways		Collagen formation Collagen degradation Collagen biosynthesis and modifying enzymes Degradation of the extracellular matrix
Drugs
Diseases
GWAS		Systemic lupus erythematosus ( 21408207)
Protein-protein Interactions		3 interactors: APP IAPP SNCA
Entrez ID		84570
HPRD ID		09886
Ensembl ID		ENSG00000188517
Uniprot IDs		A8MWQ5 Q9BXS0
PDB IDs
Enriched GO Terms of Interacting Partners?		Behavior Feeding Behavior Adult Locomotory Behavior Apoptotic Process Programmed Cell Death Cell Death Death Positive Regulation Of Peptidase Activity Negative Regulation Of Thrombin Receptor Signaling Pathway Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Norepinephrine Uptake Positive Regulation Of Hydrogen Peroxide Catabolic Process Positive Regulation Of Glutathione Peroxidase Activity Adult Behavior Synapse Organization Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Synaptic Growth At Neuromuscular Junction Locomotory Behavior Dopamine Uptake Involved In Synaptic Transmission Collateral Sprouting In Absence Of Injury Negative Regulation Of Serotonin Uptake Negative Regulation Of Dopamine Metabolic Process Negative Regulation Of Cellular Respiration Negative Regulation Of Endopeptidase Activity Negative Regulation Of Peptidase Activity Negative Regulation Of Oxidative Phosphorylation Negative Regulation Of Synaptic Transmission, Dopaminergic Positive Regulation Of Proteolysis Collateral Sprouting Axon Midline Choice Point Recognition Negative Regulation Of Proteolysis Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Response To Iron(II) Ion Cellular Response To Copper Ion Negative Regulation Of Protein Processing Extracellular Matrix Organization Extracellular Structure Organization Regulation Of Endopeptidase Activity Axon Choice Point Recognition Regulation Of Cellular Amino Acid Metabolic Process Negative Regulation Of Hydrolase Activity Regulation Of Protein Processing Regulation Of Peptidase Activity Regulation Of Synaptic Vesicle Recycling Response To Oxidative Stress Single-organism Behavior Posttranscriptional Regulation Of Gene Expression Neuron Remodeling Regulation Of Dopamine Uptake Involved In Synaptic Transmission Regulation Of Oxidative Phosphorylation
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