SLC12A8

Description		solute carrier family 12 member 8
Image		No pdb structure
GO Annotations	Cellular Component	Membrane
	Molecular Function	Protein Binding Symporter Activity Chloride:monoatomic Cation Symporter Activity Potassium:chloride Symporter Activity
	Biological Process	Monoatomic Ion Transport Potassium Ion Transport Cell Volume Homeostasis Chloride Ion Homeostasis Potassium Ion Homeostasis Transmembrane Transport Chloride Transmembrane Transport Potassium Ion Import Across Plasma Membrane
Pathways
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 33547301) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cobalt levels ( 26025379) Cortical surface area (MOSTest) ( 32665545) Fasting plasma glucose ( 31170924) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Mean spheric corpuscular volume ( 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Severe insulin-deficient type 2 diabetes ( 34737425) Subcortical volume (MOSTest) ( 32665545) Tonsillectomy ( 28928442 27182965) Type 2 diabetes ( 32499647 30297969)
Interacting Genes		1 interacting genes: PAX6
Entrez ID		84561
HPRD ID		11563
Ensembl ID		ENSG00000221955
Uniprot IDs		A0AV02
PDB IDs
Enriched GO Terms of Interacting Partners?		Forebrain-midbrain Boundary Formation Pancreatic A Cell Development Forebrain Dorsal/ventral Pattern Formation Regulation Of Asymmetric Cell Division Forebrain Neuron Fate Commitment Habenula Development Oligodendrocyte Cell Fate Specification Ventral Spinal Cord Development Pallium Development Formation Of Anatomical Boundary Iris Morphogenesis Glial Cell Fate Specification Commitment Of Neuronal Cell To Specific Neuron Type In Forebrain Cerebral Cortex Regionalization Lacrimal Gland Development Telencephalon Regionalization Type B Pancreatic Cell Differentiation Cornea Development In Camera-type Eye Salivary Gland Morphogenesis Dorsal/ventral Axis Specification HMG Box Domain Binding Co-SMAD Binding Regulation Of Timing Of Cell Differentiation Regulation Of Development, Heterochronic Negative Regulation Of Neuroblast Proliferation Embryonic Camera-type Eye Morphogenesis Enteroendocrine Cell Differentiation RNA Polymerase II Core Promoter Sequence-specific DNA Binding Negative Regulation Of Neural Precursor Cell Proliferation Histone Acetyltransferase Binding Embryonic Eye Morphogenesis R-SMAD Binding Positive Regulation Of Neuroblast Proliferation Gland Morphogenesis Pituitary Gland Development Astrocyte Differentiation Photoreceptor Cell Development Establishment Of Spindle Orientation Regulation Of Neuroblast Proliferation Lens Development In Camera-type Eye Signal Transduction Involved In Regulation Of Gene Expression Eye Photoreceptor Cell Development Transcription Coregulator Binding Neuron Fate Commitment Establishment Of Mitotic Spindle Localization Cell Fate Determination Establishment Of Mitotic Spindle Orientation Neuroblast Proliferation Positive Regulation Of Neural Precursor Cell Proliferation Establishment Of Spindle Localization
Tagcloud ?