ACSS1

Gene Name		acyl-CoA synthetase short-chain family member 1
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Gene Ontology Annotations	Cellular Component	Mitochondrial Matrix
	Molecular Function	Acetate-CoA Ligase Activity Protein Binding ATP Binding AMP Binding
	Biological Process	Ethanol Oxidation Acetyl-CoA Biosynthetic Process Xenobiotic Metabolic Process Acetate Biosynthetic Process Acetyl-CoA Biosynthetic Process From Acetate Propionate Biosynthetic Process Small Molecule Metabolic Process
Pathways		Defective CYP2R1 causes Rickets vitamin D-dependent 1B (VDDR1B) Defective FMO3 causes Trimethylaminuria (TMAU) Defective TBXAS1 causes Ghosal hematodiaphyseal dysplasia (GHDD) Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR) Defective CYP27A1 causes Cerebrotendinous xanthomatosis (CTX) Defective CYP11B1 causes Adrenal hyperplasia 4 (AH4) Defective CYP26B1 causes Radiohumeral fusions with other skeletal and craniofacial anomalies (RHFCA) Ethanol oxidation Metabolic disorders of biological oxidation enzymes Defective CYP1B1 causes Glaucoma Defective CYP27B1 causes Rickets vitamin D-dependent 1A (VDDR1A) Phase 1 - Functionalization of compounds Defective CYP17A1 causes Adrenal hyperplasia 5 (AH5) Defective CYP19A1 causes Aromatase excess syndrome (AEXS) Defective CYP7B1 causes Spastic paraplegia 5A, autosomal recessive (SPG5A) and Congenital bile acid synthesis defect 3 (CBAS3) Defective CYP4F22 causes Ichthyosis, congenital, autosomal recessive 5 (ARCI5) Defective CYP26C1 causes Focal facial dermal dysplasia 4 (FFDD4) Defective CYP24A1 causes Hypercalcemia, infantile (HCAI) Defective CYP2U1 causes Spastic paraplegia 56, autosomal recessive (SPG56) Defective MAOA causes Brunner syndrome (BRUNS) Defective CYP11B2 causes Corticosterone methyloxidase 1 deficiency (CMO-1 deficiency) Defective CYP21A2 causes Adrenal hyperplasia 3 (AH3) Biological oxidations
Drugs		Adenosine monophosphate Adenosine triphosphate
Diseases
GWAS		Cognitive performance ( 20125193)
Protein-protein Interactions		1 interactors: VAC14
Entrez ID		84532
HPRD ID		12413
Ensembl ID		ENSG00000154930
Uniprot IDs		Q1RMZ4 Q9NUB1
PDB IDs		3GLR 3GLT 3GLU 4BVE 4BVF 4BVG
Enriched GO Terms of Interacting Partners?
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