KIAA1804

Gene Name		mixed lineage kinase 4
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cellular_component
	Molecular Function	MAP Kinase Kinase Kinase Activity Protein Tyrosine Kinase Activity ATP Binding Protein Homodimerization Activity
	Biological Process	Activation Of MAPKK Activity Protein Phosphorylation Activation Of JUN Kinase Activity Peptidyl-tyrosine Phosphorylation Protein Autophosphorylation
Pathways
Drugs
Diseases
GWAS		Diabetic retinopathy ( 21441570) Periodontal microbiota ( 22699663)
Protein-protein Interactions		1 interactors: MAP3K10
Entrez ID		84451
HPRD ID		10087
Ensembl ID		ENSG00000143674
Uniprot IDs		Q5TCX8
PDB IDs
Enriched GO Terms of Interacting Partners?		Activation Of JNKK Activity Activation Of JUN Kinase Activity Peptidyl-threonine Phosphorylation Activation Of MAPKK Activity Positive Regulation Of JUN Kinase Activity Regulation Of JUN Kinase Activity JNK Cascade Smoothened Signaling Pathway Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Stress-activated MAPK Cascade Peptidyl-serine Phosphorylation Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of JNK Cascade Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Activation Of MAPK Activity Regulation Of JNK Cascade Regulation Of Stress-activated MAPK Cascade Protein Autophosphorylation Positive Regulation Of MAP Kinase Activity MAPK Cascade
Tagcloud ?		3p 3q abcc5 agtr1 amplifications bcl6 beadarray beadarraytrade cdkn2a cdkn2b coincidently csf1 ctnnb1 dnas dvl3 esophageal fancd2 ffpe fgf12 hapmap il2 irf7 map3k9 mlf1 ntrk2 pms2 prkar1a tnfsf10 tnk2