CASQ1

Name	calsequestrin 1
Structure
Interactors	1 interactors: TRDN
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix Endoplasmic Reticulum Smooth Endoplasmic Reticulum Terminal Cisterna Terminal Cisterna Lumen Membrane Sarcoplasmic Reticulum Myofibril Z Disc T-tubule I Band Sarcoplasmic Reticulum Membrane Sarcoplasmic Reticulum Lumen Sarcolemma
	Molecular Function	Calcium Ion Binding Protein Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Endoplasmic Reticulum Organization Skeletal Muscle Tissue Development Response To Heat Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Skeletal Muscle Contraction By Regulation Of Release Of Sequestered Calcium Ion Response To Muscle Inactivity Response To Denervation Involved In Regulation Of Muscle Adaptation Sarcomere Organization Protein Polymerization Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Regulation Of Sequestering Of Calcium Ion Positive Regulation Of Store-operated Calcium Channel Activity Regulation Of Store-operated Calcium Entry
Pathways	Stimuli-sensing channels Ion homeostasis
Drugs	Calcium citrate Calcium Phosphate Calcium levulinate Calcium phosphate dihydrate
GWAS	No GWAS studies recorded
Entrez ID	844
HPRD ID	15915
Ensembl ID	ENSG00000143318
Uniprot IDs	P31415
PDB IDs	3UOM 5CRD 5CRE 5CRG 5CRH 8F48
GO Terms Enriched among Interactors ?	Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Positive Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Sarcoplasmic Reticulum Lumen Positive Regulation Of Cell Communication By Electrical Coupling Junctional Sarcoplasmic Reticulum Membrane Regulation Of Cardiac Muscle Cell Membrane Potential Release Of Sequestered Calcium Ion Into Cytosol By Endoplasmic Reticulum Junctional Membrane Complex Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Regulation Of Cell Communication By Electrical Coupling Sarcoplasmic Reticulum Calcium Ion Transport Endoplasmic Reticulum Membrane Organization Heart Contraction Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Heart Process Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Sarcoplasmic Reticulum Membrane Release Of Sequestered Calcium Ion Into Cytosol Negative Regulation Of Sequestering Of Calcium Ion Cytoplasmic Microtubule Organization Sarcoplasmic Reticulum Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Regulation Of Cardiac Muscle Contraction Calcium Ion Transmembrane Import Into Cytosol Regulation Of Striated Muscle Contraction Regulation Of Sequestering Of Calcium Ion Transmembrane Transporter Binding Regulation Of Calcium Ion Transmembrane Transport Regulation Of Muscle Contraction Calcium-mediated Signaling Regulation Of Heart Contraction Muscle Contraction Intracellular Calcium Ion Homeostasis Calcium Ion Transmembrane Transport Protein-macromolecule Adaptor Activity Calcium Ion Homeostasis Regulation Of Calcium Ion Transport Regulation Of Blood Circulation Muscle System Process Regulation Of Muscle System Process Calcium Ion Transport Regulation Of Monoatomic Cation Transmembrane Transport Regulation Of Monoatomic Ion Transmembrane Transport Circulatory System Process