HVCN1

Description		hydrogen voltage gated channel 1
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GO Annotations	Cellular Component	Plasma Membrane Cilium Membrane Apical Plasma Membrane Secretory Granule Membrane Phagocytic Vesicle Membrane Cytoplasmic Vesicle Motile Cilium Monoatomic Ion Channel Complex Specific Granule Membrane Sperm Flagellum Cell Projection
	Molecular Function	Monoatomic Ion Channel Activity Protein Binding Voltage-gated Monoatomic Cation Channel Activity Voltage-gated Proton Channel Activity Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Immune System Process Monoatomic Ion Transport Single Fertilization Response To PH Response To Zinc Ion Monoatomic Ion Transmembrane Transport Innate Immune Response Cell Redox Homeostasis Regulation Of Intracellular PH Transmembrane Transport Regulation Of Acrosome Reaction Cellular Response To Zinc Ion Cellular Response To PH Proton Transmembrane Transport Regulation Of Reactive Oxygen Species Biosynthetic Process
Pathways		ROS and RNS production in phagocytes Sperm Motility And Taxes Neutrophil degranulation
Drugs
Diseases
GWAS		Composite immunoglobulin trait (IgA/IgG) ( 28628107) Red blood cell count ( 32888494)
Interacting Genes		1 interacting genes: CREB3
Entrez ID		84329
HPRD ID		17507
Ensembl ID		ENSG00000122986
Uniprot IDs		Q96D96
PDB IDs		3A2A 5OQK
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Deacetylase Activity CCR1 Chemokine Receptor Binding Release From Viral Latency CAMP Response Element Binding Protein Binding Induction Of Positive Chemotaxis Positive Regulation Of Monocyte Chemotaxis Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Positive Chemotaxis Regulation Of Monocyte Chemotaxis Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Transcription Coregulator Binding Integrated Stress Response Signaling Negative Regulation Of Response To Endoplasmic Reticulum Stress Endoplasmic Reticulum Unfolded Protein Response Positive Regulation Of Mononuclear Cell Migration Response To Unfolded Protein Regulation Of Response To Endoplasmic Reticulum Stress Positive Regulation Of Leukocyte Chemotaxis Positive Regulation Of Calcium Ion Transport Negative Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Mononuclear Cell Migration Positive Regulation Of Leukocyte Migration Positive Regulation Of Chemotaxis Viral Process RNA Polymerase II Transcription Regulator Complex
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