CCDC77

Description		coiled-coil domain containing 77
Image		No pdb structure
GO Annotations	Cellular Component	Centrosome Membrane
	Molecular Function
	Biological Process
Pathways
Drugs
Diseases
GWAS		Alcohol consumption (max-drinks) ( 29460428) Body mass index ( 26426971) Metabolite levels ( 23823483) Obesity (early onset extreme) ( 23563609) Peak height velocity ( 34047840) Thyroid stimulating hormone levels ( 32769997) Type 2 diabetes ( 30054458)
Interacting Genes		2 interacting genes: MCPH1 OGT
Entrez ID		84318
HPRD ID		17485
Ensembl ID		ENSG00000120647
Uniprot IDs		Q9BR77
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Non-canonical Inflammasome Complex Assembly Positive Regulation Of Transcription By Glucose Carbon Catabolite Regulation Of Transcription Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Protein O-acetylglucosaminyltransferase Activity Regulation Of Transcription By Glucose NSL Complex Protein Localization To Organelle Regulation Of Chromosome Condensation Mitophagy Protein Localization To Lysosome Circadian Regulation Of Gene Expression Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Stem Cell Population Maintenance Cellular Response To Glucose Stimulus Acetylglucosaminyltransferase Activity Negative Regulation Of RNA Metabolic Process Regulation Of Stem Cell Population Maintenance Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Histone Acetyltransferase Complex Regulation Of Carbohydrate Catabolic Process Sin3-type Complex Regulation Of Gluconeogenesis Negative Regulation Of DNA-templated Transcription Regulation Of ATP Metabolic Process Regulation Of Glycolytic Process Positive Regulation Of TORC1 Signaling Cellular Response To Carbohydrate Stimulus Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Necroptotic Process Negative Regulation Of Translational Initiation Negative Regulation Of Proteasomal Protein Catabolic Process Regulation Of Receptor Localization To Synapse Regulation Of Protein Localization To Synapse Regulation Of Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Phosphatidylinositol-3,4,5-trisphosphate Binding Pyroptotic Inflammatory Response Cellular Response To Nutrient Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Autophagy Of Mitochondrion Positive Regulation Of Translational Initiation Regulation Of Rac Protein Signal Transduction Negative Regulation Of Protein Ubiquitination TORC1 Signaling Negative Regulation Of Stem Cell Population Maintenance Regulation Of Insulin Receptor Signaling Pathway Negative Regulation Of RNA Biosynthetic Process
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