RNF135

Gene Name		ring finger protein 135
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ligase Activity Ribonucleoprotein Complex Binding
	Biological Process	Protein Ubiquitination Negative Regulation Of Type I Interferon Production Positive Regulation Of Interferon-beta Production Innate Immune Response Regulation Of Innate Immune Response
Pathways		TRAF3-dependent IRF activation pathway RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways Negative regulators of RIG-I/MDA5 signaling TRAF6 mediated IRF7 activation TRAF6 mediated NF-kB activation NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 Innate Immune System
Drugs
Diseases
GWAS		Height ( 18391951)
Protein-protein Interactions		5 interactors: CTNNAL1 DDX58 GOLGA2 RARRES3 UBE2D2
Entrez ID		84282
HPRD ID		11506
Ensembl ID		ENSG00000181481
Uniprot IDs		B3KV69 Q8IUD6
PDB IDs
Enriched GO Terms of Interacting Partners?		Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Positive Regulation Of Innate Immune Response RIG-I Signaling Pathway Regulation Of Type III Interferon Production Detection Of Virus Regulation Of Innate Immune Response Cytoplasmic Pattern Recognition Receptor Signaling Pathway In Response To Virus Cellular Response To Virus Positive Regulation Of Defense Response To Virus By Host Immune Response-regulating Signaling Pathway Positive Regulation Of Interferon-alpha Production Positive Regulation Of Interferon-beta Production Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Regulation Of Defense Response To Virus By Host Positive Regulation Of Immune Response
Tagcloud ?		asians blacks brd3 challenges childhood crlf2 cured differ differentially disparities distributed erbb2 erbb3 ethnic exist follows hispanics implicated lymphoblastic networks pdgf pediatric persist phf6 pi3 populations racial united whites