C9orf89

Gene Name		chromosome 9 open reading frame 89
Image
Gene Ontology Annotations	Cellular Component	Nucleus Endoplasmic Reticulum Membrane Cytosol Integral Component Of Membrane Mitochondrial Membrane
	Molecular Function	CARD Domain Binding
	Biological Process	Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		1 interactors: BCL10
Entrez ID		84270
HPRD ID		12985
Ensembl ID		ENSG00000165233
Uniprot IDs		Q96LW7
PDB IDs		4DWN 4FH0
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Mast Cell Cytokine Production Lymphotoxin A Biosynthetic Process Interleukin-6 Biosynthetic Process Negative Regulation Of Mature B Cell Apoptotic Process Interleukin-6 Production Positive Regulation Of Interleukin-8 Biosynthetic Process B Cell Apoptotic Process Negative Regulation Of B Cell Apoptotic Process Regulation Of Interleukin-8 Biosynthetic Process T Cell Apoptotic Process Regulation Of B Cell Apoptotic Process Response To Food Cytokine Biosynthetic Process Positive Regulation Of Myeloid Leukocyte Cytokine Production Involved In Immune Response Cytokine Metabolic Process Positive Regulation Of Interleukin-8 Production Response To Fungus Regulation Of T Cell Receptor Signaling Pathway Positive Regulation Of Cytokine Production Involved In Immune Response Cellular Defense Response Negative Regulation Of Leukocyte Apoptotic Process Regulation Of Lymphocyte Apoptotic Process Positive Regulation Of Cytokine Biosynthetic Process Cellular Response To Mechanical Stimulus Regulation Of Cytokine Production Involved In Immune Response Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Neural Tube Closure Toll-like Receptor Signaling Pathway T Cell Receptor Signaling Pathway Regulation Of Cytokine Biosynthetic Process Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of Cysteine-type Endopeptidase Activity Neural Tube Formation Pattern Recognition Receptor Signaling Pathway Positive Regulation Of Endopeptidase Activity Innate Immune Response-activating Signal Transduction Positive Regulation Of Protein Ubiquitination Antigen Receptor-mediated Signaling Pathway Cytokine Production Activation Of Innate Immune Response Embryonic Epithelial Tube Formation Positive Regulation Of Peptidase Activity Epithelial Tube Formation Tube Formation Morphogenesis Of Embryonic Epithelium Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Immunoglobulin Mediated Immune Response B Cell Mediated Immunity Positive Regulation Of Innate Immune Response
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