FAR1

Description		fatty acyl-CoA reductase 1
Image		No pdb structure
GO Annotations	Cellular Component	Peroxisome Peroxisomal Membrane Membrane
	Molecular Function	Protein Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On The Aldehyde Or Oxo Group Of Donors, NAD Or NADP As Acceptor Alcohol-forming Very Long-chain Fatty Acyl-CoA Reductase Activity Alcohol-forming Long-chain Fatty Acyl-CoA Reductase Activity
	Biological Process	Lipid Metabolic Process Lipid Biosynthetic Process Ether Lipid Biosynthetic Process Wax Biosynthetic Process Long-chain Fatty-acyl-CoA Metabolic Process Glycerophospholipid Biosynthetic Process Fatty Acid Derivative Metabolic Process
Pathways		Wax biosynthesis
Drugs
Diseases
GWAS		Childhood ear infection ( 27182965) Common carotid intima-media thickness in HIV negative individuals ( 29206233) Night sleep phenotypes ( 27126917) Response to TNF inhibitor in rheumatoid arthritis (change in swollen 28-joint count) ( 30166627) Response to TNF inhibitor in rheumatoid arthritis (change in tender 28-joint count) ( 30166627) Schizophrenia x sex interaction ( 34099189) Visceral adipose tissue adjusted for BMI ( 26480920)
Interacting Genes		2 interacting genes: ATXN1 SLC2A4
Entrez ID		84188
HPRD ID		14724
Ensembl ID		ENSG00000197601
Uniprot IDs		Q8WVX9
PDB IDs
Enriched GO Terms of Interacting Partners?		Memory Amylopectin Biosynthetic Process D-glucose Uniporter Activity Regulation Of Synaptic Vesicle Budding From Presynaptic Endocytic Zone Membrane Learning Or Memory Positive Regulation Of Brain-derived Neurotrophic Factor Receptor Signaling Pathway Cognition POZ Domain Binding White Fat Cell Proliferation Insulin-responsive Compartment Glucose Import In Response To Insulin Stimulus Poly(G) Binding Dehydroascorbic Acid Transport Fat Cell Proliferation Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway D-glucose Transmembrane Transporter Activity Nuclear Inclusion Body Short-term Memory Trans-Golgi Network Transport Vesicle D-glucose Import Poly(U) RNA Binding Positive Regulation Of Glial Cell Proliferation Nervous System Process Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Brown Fat Cell Differentiation D-glucose Transmembrane Transport Insulin-like Growth Factor Receptor Signaling Pathway Long-term Memory Hexose Transmembrane Transport Vesicle Membrane Regulation Of Glial Cell Proliferation Lung Alveolus Development Cellular Response To Osmotic Stress Carbohydrate Transport Vitamin Transport Carbohydrate Transmembrane Transport T-tubule Multivesicular Body Visual Learning Social Behavior Visual Behavior Excitatory Postsynaptic Potential Macromolecule Biosynthetic Process System Process Positive Regulation Of Gliogenesis Sarcoplasmic Reticulum Clathrin-coated Pit Response To Osmotic Stress Adult Locomotory Behavior Clathrin-coated Vesicle
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