USP42

Gene Name		ubiquitin specific peptidase 42
Image		No pdb structure
Gene Ontology Annotations	Cellular Component
	Molecular Function	Cysteine-type Endopeptidase Activity Ubiquitin-specific Protease Activity Protein Binding
	Biological Process	Spermatogenesis Protein Deubiquitination Cell Differentiation Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		2 interactors: SPP1 TP53
Entrez ID		84132
HPRD ID		18879
Ensembl ID		ENSG00000106346
Uniprot IDs		Q9H9J4
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Tissue Remodeling Negative Regulation Of Cell Growth Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Negative Regulation Of Growth Negative Regulation Of Neurogenesis Negative Regulation Of Macromitophagy Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Oligodendrocyte Apoptotic Process Negative Regulation Of Cell Development Regulation Of Cell Growth Negative Regulation Of Helicase Activity Response To Nutrient Levels Response To Extracellular Stimulus Positive Regulation Of Cell Aging Positive Regulation Of Thymocyte Apoptotic Process Negative Regulation Of Collateral Sprouting Mitochondrial DNA Repair Negative Regulation Of Axon Regeneration Regulation Of Mitochondrion Degradation T Cell Proliferation Involved In Immune Response B Cell Lineage Commitment Glial Cell Apoptotic Process Oxidative Stress-induced Premature Senescence Regulation Of Growth ER Overload Response Negative Regulation Of Macroautophagy Stress-induced Premature Senescence Regulation Of Neurogenesis Negative Regulation Of Cell Differentiation Positive Regulation Of T Cell Apoptotic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator DNA Strand Renaturation DNA Damage Response, Signal Transduction Resulting In Transcription Mitotic Cell Cycle Arrest Positive Regulation Of Cardiac Muscle Cell Apoptotic Process Positive Regulation Of Bone Resorption Regulation Of Thymocyte Apoptotic Process Regulation Of Cell Development Replicative Senescence Positive Regulation Of Mitochondrial Membrane Permeability Determination Of Adult Lifespan Positive Regulation Of Lymphocyte Apoptotic Process Circadian Behavior Regulation Of Axon Regeneration Mitochondrial DNA Metabolic Process Positive Regulation Of Histone Deacetylation Rhythmic Behavior Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of Fibroblast Apoptotic Process Positive Regulation Of Protein Oligomerization
Tagcloud ?		basal bound co consistent contribute depletion deubiquitylated deubiquitylating enzyme foci h2b histones ii independently localized nuclear p53 peptidase pol polymerase promoter promoters regulate regulating rna stabilization transcription ubiquitin ubiquitylation