CEP78

Description		centrosomal protein 78
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Centriole Cytosol Cytoskeleton Cilium Ciliary Basal Body Cell Projection
	Molecular Function
	Biological Process	Cell Projection Organization Flagellated Sperm Motility Negative Regulation Of Protein Ubiquitination Cilium Organization Protein Localization To Cilium Protein Localization To Centrosome
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases
GWAS
Interacting Genes		3 interacting genes: HSPB1 SH3BP4 UBC
Entrez ID		84131
HPRD ID		19359
Ensembl ID		ENSG00000148019
Uniprot IDs		A0A2R8YCP0 A8MST6 Q5JTW2
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Protein Kinase C Signaling Positive Regulation Of Endothelial Cell Chemotaxis Protein Transport Along Microtubule Negative Regulation Of Protein Kinase C Signaling Extracellular Exosome Anterograde Axonal Protein Transport Protein Kinase C Inhibitor Activity Contractile Muscle Fiber Regulation Of Autophagy Protein Tag Activity Amino Acid Import GDP-dissociation Inhibitor Activity Negative Regulation Of GTPase Activity
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